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Barrett, Hugh

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Publication DateTitleAuthor(s)Date Added
1Oct-2022Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose–response modelJadhav, Satyawan B; Crass, Ryan L; Chapel, Sunny; Kerschnitzki, Michael; Sasiela, William J; Emery, Maurice G; Amore, Benny M; Barrett, P Hugh R ; Watts, Gerald F; Catapano, Alberico L6-Oct-2023
2Jun-2022PCSK9 inhibition with alirocumab decreases plasma lipoprotein(a) concentration by a dual mechanism of action in statin‐treated patients with very high apolipoprotein(a) concentrationYing, Qidi; Chan, Dick C; Pang, Jing; Marcovina, Santica M; Barrett, Peter Hugh R ; Watts, Gerald F12-May-2022
31-Nov-2021Unravelling lipoprotein metabolism with stable isotopes: tracing the flowYing, Qidi; Chan, Dick C; Barrett, P Hugh R ; Watts, Gerald F9-Mar-2022
41-Jun-2020PCSK9 Inhibition with alirocumab increases the catabolism of lipoprotein(a) particles in statin-treated patients with elevated lipoprotein(a)Watts, Gerald F; Chan, Dick C; Pang, Jing; Ma, Louis; Ying, Qidi; Aggarwal, Shashi; Marcovina, Santica M; Barrett, P Hugh R 16-Aug-2021
5Dec-2019Apolipoprotein(a) Kinetics in Statin-Treated Patients With Elevated Plasma Lipoprotein(a) ConcentrationMa, Louis; Chan, Dick C; Ooi, Esther M M; Marcovina, Santica M; Barrett, P Hugh R ; Watts, Gerald F18-Aug-2021
61-Jul-2019Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentrationMa, Louis; Chan, Dick C; Ooi, Esther M M; Barrett, P Hugh R ; Watts, Gerald F17-Aug-2021
72-Apr-2019Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol-Lowering TherapyChan, Dick C; Watts, Gerald F; Coll, Blai; Wasserman, Scott M; Marcovina, Santica M; Barrett, P Hugh R 16-Aug-2021
8Feb-2019Lipoprotein (a) and Low-density lipoprotein apolipoprotein B metabolism following apheresis in patients with elevated lipoprotein(a) and coronary artery diseaseMa, Louis; Waldmann, Elisa; Ooi, Esther M M; Chan, Dick C; Barrett, Hugh P R ; Watts, Gerald F; Parhofer, Klaus G17-Aug-2021
91-Aug-2018Lipoprotein(a) and apolipoprotein(a) isoform size: Associations with angiographic extent and severity of coronary artery disease, and carotid artery plaqueOoi, Esther MM; Ellis, Katrina L; Barrett, P Hugh R ; Watts, Gerald F; Hung, Joseph; Beilby, John P; Thompson, Peter L; Stobie, Paul; McQuillan, Brendan M11-Aug-2021
1014-Jul-2018Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kineticsWatts, Gerald F; Chan, Dick C; Somaratne, Ransi; Wasserman, Scott M; Scott, Rob; Marcovina, Santica M; Barrett, P Hugh R 11-Aug-2021
11Jul-2018Comparative Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibition and Statins on Postprandial Triglyceride-Rich Lipoprotein MetabolismChan, Dick C; Watts, Gerald F; Somaratne, Ransi; Wasserman, Scott M; Scott, Rob; Barrett, P Hugh R 28-Mar-2019
12May-2018Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient (LDLR+/− and LDLR−/−) Yucatan Miniature PigsBurke, Amy C; Telford, Dawn E; Sutherland, Brian G; Edwards, Jane Y; Sawyez, Cynthia G; Barrett, P Hugh R ; Newton, Roger S; Pickering, J Geoffrey; Huff, Murray W11-Aug-2021
13Apr-2018Acute Impact of Different Exercise Modalities on Arterial and Platelet FunctionHaynes, Andrew; Linden, Matthew D; Robey, Elisa; Watts, Gerald F; Barrett, P Hugh R ; Naylor, Louise H; Green, Daniel J8-Mar-2022
14Feb-2018Differential Effects of Estrogen and Progestin on Apolipoprotein B100 and B48 Kinetics in Postmenopausal WomenLamon-Fava, Stefania; Diffenderfer, Margaret R; Barrett, P Hugh R ; Wan, Wing Yee; Postfai, Borbala; Nartsupha, Chorthip; Dolnikowski, Gregory G; Schaefer, Ernst J11-Aug-2021
15Aug-2017Tamoxifen reduces hepatic VLDL production and GH secretion in women: a possible mechanism for steatosis developmentBirzniece, Vita; Barrett, P Hugh R ; Ho, Ken K Y11-Aug-2021
16Jul-2017Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatinThongtang, Nuntakorn; Diffenderfer, Margaret R; Ooi, Esther M M; Barrett, P Hugh R ; Turner, Scott M; Le, Ngoc-Anh; Brown, W Virgil; Schaefer, Ernst J4-Feb-2022
172-Mar-2017Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLDMardinoglu, Adil; Bjornson, Elias; Zhang, Cheng; Klevstig, Martina; Soderlund, Sanni; Stahlman, Marcus; Adiels, Martin; Hakkarainen, Antti; Lundbom, Nina; Kilicarslan, Murat; Hallstrom, Bjorn M; Lundbom, Jesper; Verges, Bruno; Barrett, Peter Hugh R ; Watts, Gerald F; Serlie, Mireille J; Nielsen, Jens; Uhlen, Mathias; Smith, Ulf; Marschall, Hanns-Ulrich; Taskinen, Marja-Riitta; Boren, Jan20-Mar-2022
1824-Jan-2017Factorial Effects of Evolocumab and Atorvastatin on Lipoprotein MetabolismWatts, Gerald F; Chan, Dick C; Dent, Ricardo; Somaratne, Ransi; Wasserman, Scott M; Scott, Rob; Burrows, Sally; Barrett, P Hugh R 16-Aug-2021
19Dec-2016Effect of omega-3 fatty acid supplementation on arterial elasticity in patients with familial hypercholesterolaemia on statin therapyChan, D C; Pang, J; Barrett, P H R ; Sullivan, D R; Mori, T A; Burnett, J R; van Bockxmeer, F M; Watts, G F3-Feb-2022
20Dec-2016Recent explanatory trials of the mode of action of drug therapies on lipoprotein metabolismChan, Dick C; Barrett, P Hugh R ; Watts, Gerald F9-Mar-2022
211-Oct-2016ω-3 Fatty Acid Ethyl Esters Diminish Postprandial Lipemia in Familial HypercholesterolemiaChan, Dick C; Pang, Jing; Barrett, P Hugh R ; Sullivan, David R; Burnett, John R; van Bockxmeer, Frank M; Watts, Gerald F9-Mar-2022
22Oct-2016Impact of commonly prescribed exercise interventions on platelet activation in physically inactive and overweight menHaynes, Andrew; Linden, Matthew D; Robey, Elisa; Watts, Gerald F; Barrett, Hugh ; Naylor, Louise H; Green, Daniel J10-Mar-2022
23Aug-2016Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-IIIOoi, Esther M; Chan, Dick C; Hodson, Leanne; Adiels, Martin; Boren, Jan; Karpe, Fredrik; Fielding, Barbara A; Watts, Gerald F; Barrett, P Hugh R 9-Mar-2022
24Jun-2016Lipoprotein metabolism in an apoB-80 familial hypobetalipoproteinemia heterozygoteHooper, Amanda J; Robertson, Ken; Champain, Danie; Hua, Jianmin; Song, Swithin; Parhofer, Klaus G; Barrett, P Hugh R ; van Bockxmeer, Frank M; Burnett, John R9-Mar-2022
251-May-2016Modeling the Male Reproductive Endocrine Axis: Potential Role for a Delay Mechanism in the Inhibitory Action of Gonadal Steroids on GnRH Pulse FrequencyFerasyi, Teuku R; Barrett, P Hugh R ; Blache, Dominique; Martin, Graeme B13-Mar-2022
26May-2016Plasma Proprotein Convertase Subtilisin Kexin Type 9 as a Predictor of Carotid Atherosclerosis in Asymptomatic AdultsChan, Dick C; Pang, Jing; McQuillan, B M; Hung, Joseph; Beilby, John P; Barrett, P Hugh R ; Watts, Gerald F10-Mar-2022
271-Apr-2016ApoA-II HDL catabolism and its relationships with the kinetics of ApoA-I HDL and of VLDL1, in abdominal obesityVergès, Bruno; Adiels, Martin; Boren, Jan; Barrett, Peter Hugh ; Watts, Gerald F; Chan, Dick; Duvillard, Laurence; Söderlund, Sanni; Matikainen, Niina; Kahri, Juhani; Lundbom, Nina; Lundbom, Jesper; Hakkarainen, Antti; Aho, Serge; Simoneau-Robin, Isabelle; Taskinen, Marja-Riitta10-Mar-2022
28Apr-2016Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a)Diffenderfer, Margaret R; Lamon-Fava, Stefania; Marcovina, Santica M; Barrett, P Hugh R ; Lel, Julian; Dolnikowski, Gregory G; Berglund, Lars; Schaefer, Ernst J9-Mar-2022
29Apr-2016Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetesPang, J; Chan, D C; Hamilton, S J; Tenneti, V S; Watts, Gerald F; Barrett, P Hugh R 10-Mar-2022
30Dec-2015Effects of Extended-Release Niacin on the Postprandial Metabolism of Lp(a) and ApoB-100-Containing Lipoproteins in Statin-Treated Men with Type 2 Diabetes MellitusOoi, Esther M; Watts, Gerald F; Chan, Dick C; Pang, Jing; Tenneti, Vijay S; Hamilton, Sandra J; McCormick, Sally P; Marcovina, Santica M; Barrett, P Hugh R 17-May-2022
311-Nov-2015Lipoprotein metabolism in APOB L343V familial hypobetalipoproteinemiaHooper, Amanda J; Heeks, Liesl; Robertson, Ken; Champain, Danie; Hua, Jianmin; Song, Swithin; Parhofer, Klaus G; Barrett, P Hugh R ; Van Bockxmeer, Frank M; Burnett, John R16-May-2022
3227-Oct-2015Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in WomenHodson, Leanne; Banerjee, Rajahshi; Rial, Belén; Arlt, Wiebke; Adiels, Martin; Boren, Jan; Marinou, Kyriakoula; Fisher, Ciaran; Mostad, Ingrid L; Stratton, Irene M; Barrett, P Hugh R ; Chan, Dick C; Watts, Gerald F; Harnden, Karin; Karpe, Fredrik; Fielding, Barbara A14-Mar-2022
33Oct-2015Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity: Multicenter Tracer Kinetic StudyBorén, Jan; Watts, Gerald F; Adiels, Martin; Söderlund, Sanni; Chan, Dick C; Hakkarainen, Antti; Lundbom, Jesper; Lundbom, Nina; Matikainen, Niina; Kahri, Juhani; Vergès, Bruno; Barrett, P Hugh R ; Taskinen, Marja-Riitta17-May-2022
341-Jun-2015Association of Plasma Ceramides and Sphingomyelin With VLDL apoB-100 Fractional Catabolic Rate Before and After Rosuvastatin TreatmentNg, Theodore W K; Ooi, Esther M M; Watts, Gerald F; Chan, Dick C; Meikle, Peter J; Barrett, P Hugh R 16-May-2022
35Jun-2015Effect of dietary fatty acids on human lipoprotein metabolism: A comprehensive updateOoi, Esther M; Watts, Gerald F; Ng, Theodore W K; Barrett, P Hugh R 17-May-2022
36May-2015Rosuvastatin Enhances the Catabolism of LDL apoB-100 in Subjects with Combined Hyperlipidemia in a Dose Dependent MannerLe, Ngoc‑Anh; Diffenderfer, Margaret R; Thongtang, Nuntakorn; Ooi, Esther M M; Barrett, P Hugh R ; Horvath, Katalin V; Dolnikowski, Gregory G; Asztalos, Bela F; Schaefer, Ernst J; Brown Virgil, W13-Mar-2022
37Mar-2015Inter-relationships between proprotein convertase subtilisin/kexin type 9, apolipoprotein C-III and plasma apolipoprotein B-48 transport in obese subjects: A stable isotope study in the postprandial stateChan, Dick C; Wong, Annette T Y; Pang, Jing; Barrett, P Hugh R ; Watts, Gerald F17-May-2022
38Aug-2008Dose-Dependent Effect of Rosuvastatin on VLDL-Apolipoprotein C-III Kinetics in the Metabolic SyndromeOoi, Esther M M; Watts, Gerald F; Chan, Dick C; Chen, Meifania M; Nestel, Paul J; Sviridov, Dmitri; Barrett, P Hugh R 26-May-2021
3919-Jun-2008Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein (Apo) A-I and ApoB-Containing LipoproteinsLamon-Fava, Stefania; Diffenderfer, Margaret R; Barrett, P Hugh R ; Buchsbaum, Aaron; Nyaku, Mawuli; Horvath, Katalin V; Asztalos, Bela F; Otokozawa, Seiko; Ai, Masumi; Matthan, Nirupa R; Lichtenstein, Alice H; Dolnikowski, Gregory G; Schaefer, Ernst J1-Apr-2019

Profile

Full Name
Barrett, Hugh
Variants
P H Barrett
Barrett, P Hugh R
Barrett, P H R
Barrett, Hugh P R
Barrett, Peter Hugh
 
UNE Researcher ID
une-id:pbarret6
 
Position Title
Associate Dean Research
 
Email
 
ORCID
Google Scholar profile key
7OtfUxcAAAAJ
Biography
Hugh has been a biomedical research fellow for much of his career, supported via the NIH, National Heart Foundation, NHMRC and industry. His research has focussed on lipid and lipoprotein metabolism combined with mathematical modelling, using compartment models. His research career began at the BakerIDI, moved to the University of Washington and more recently the University of Western Australia, where he was also the Associate Dean, Research in the Faculty of Health and Medical Sciences. His research has contributed to understanding lipid and lipoprotein metabolism in a variety of human dyslipidemic states and under various interventions designed to reduce cardiovascular disease burden. Using tracer methodologies his research has described the mechanism of action of statins, fibrates, CETP inhibitors, new PPAR agonists and other lipid lowering agents on lipoprotein kinetics, primarily in subjects with the metabolic syndrome. In addition, his research and modelling of tracer data in human, animal and in vitro systems has provided insight into the pathways that are responsible for the regulation of lipid metabolism. His present role is focussed on building research capacity, quality, output and outcomes in the Faculty of Medicine and Health at UNE.
 
Discipline
Faculty of Medicine and Health
 
Faculty
Faculty of Medicine and Health
Honorific
Professor
 
Surname
Barrett
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Given Name
Peter
 
Middle Name
Hugh
Preferred Given Name
Hugh
School/Department
Faculty of Medicine and Health
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