The impacts of Ascaridia galli on performance, health, and immune responses of laying hens: new insights into an old problem

Abstract

Gastrointestinal nematodes are re-emerging in countries where the popularity of free-range poultry production systems is increasing. Amongst all gastrointestinal nematodes, <i>Ascaridia galli</i> is of significant concern due to the parasite's direct life cycle and ability to survive extreme environmental conditions. In laying hens, <i>A. galli</i> parasites have been associated with reduced health, welfare, immunity, and egg production. Direct losses are caused by obstruction and damage of the intestinal tract in hens when high worm burdens are present. These result in reduction in egg production and body weight of infected laying hens, consequently leading to significant economic losses for farmers. Furthermore, heavy infections with <i>A. galli</i> may lead to increased mortality within the flock. Indirect losses are due to suppression of immune system function which can increase susceptibility to secondary infections. Infection with <i>A. galli</i> can also alter nutrient utilization and absorption. Levels of anti- <i>A. galli</i> serum and egg yolk antibodies increase following <i>A. galli</i> infection. Elevated antibodies can be used as an indicator of current or previous infections and therefore can be used as a diagnostic tool. The impact of <i>A. galli</i> on hen health and welfare manifests through the depletion of liver lipid reserves and increased use of energy reserves to mount immune responses against the parasite. This review highlights the variable effects of <i>A. galli</i> infection on the performance, health, egg quality, and emphasizes especially on immune responses of free-range laying hens as well as it evaluates various potential detection methods and preventive and control measures of this parasitic disease.