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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/9265
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dc.contributor.authorMacreadie, Peteren
dc.contributor.authorAvery, Thomas Den
dc.contributor.authorGreatrex, Benen
dc.contributor.authorTaylor, Dennis Ken
dc.contributor.authorMacreadie, Ian Gen
dc.date.accessioned2012-01-20T14:28:00Z-
dc.date.issued2006-
dc.identifier.citationBioorganic & Medicinal Chemistry Letters, 16(4), p. 920-922en
dc.identifier.issn1464-3405en
dc.identifier.issn0960-894Xen
dc.identifier.urihttps://hdl.handle.net/1959.11/9265-
dc.description.abstractFifteen new endoperoxides have been synthesised and tested for activity against pathogenic 'Candida' species. These endoperoxides can be prepared in high yields, in one to three steps, from inexpensive starting materials. Despite chemical and structural similarities, their inhibitory activity against 'Candida' growth varied greatly from one endoperoxide to another, and one species to another. This study of susceptibility to endoperoxide compounds presented here may lead to the development of potent new antifungal agents.en
dc.languageenen
dc.publisherPergamon Pressen
dc.relation.ispartofBioorganic & Medicinal Chemistry Lettersen
dc.titleNovel endoperoxides: Synthesis and activity against 'Candida' speciesen
dc.typeJournal Articleen
dc.identifier.doi10.1016/j.bmcl.2005.10.101en
dc.subject.keywordsBiologically Active Moleculesen
dc.subject.keywordsOrganic Chemical Synthesisen
local.contributor.firstnamePeteren
local.contributor.firstnameThomas Den
local.contributor.firstnameBenen
local.contributor.firstnameDennis Ken
local.contributor.firstnameIan Gen
local.subject.for2008030401 Biologically Active Moleculesen
local.subject.for2008030503 Organic Chemical Synthesisen
local.subject.seo2008970103 Expanding Knowledge in the Chemical Sciencesen
local.subject.seo2008970106 Expanding Knowledge in the Biological Sciencesen
local.profile.schoolSchool of Rural Medicineen
local.profile.emailbgreatre@une.edu.auen
local.profile.emaildennis.taylor@adelaide.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20110325-142836en
local.publisher.placeUnited Kingdomen
local.format.startpage920en
local.format.endpage922en
local.identifier.scopusid30344465331en
local.peerreviewedYesen
local.identifier.volume16en
local.identifier.issue4en
local.title.subtitleSynthesis and activity against 'Candida' speciesen
local.contributor.lastnameMacreadieen
local.contributor.lastnameAveryen
local.contributor.lastnameGreatrexen
local.contributor.lastnameTayloren
local.contributor.lastnameMacreadieen
dc.identifier.staffune-id:bgreatreen
local.profile.orcid0000-0002-0356-4966en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:9456en
dc.identifier.academiclevelAcademicen
local.title.maintitleNovel endoperoxidesen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorMacreadie, Peteren
local.search.authorAvery, Thomas Den
local.search.authorGreatrex, Benen
local.search.authorTaylor, Dennis Ken
local.search.authorMacreadie, Ian Gen
local.uneassociationUnknownen
local.year.published2006en
Appears in Collections:Journal Article
School of Rural Medicine
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