A genome-wide association study (GWAS) for carcass traits in Hanwoo cattle using imputed whole genome sequence data

Abstract

<p>The identification of genomic region that are associated with phenotypic traits differences is important for improving genomic prediction accuracy. In this study, we aimed to find significant genomic regions for carcass traits in Hanwoo cattle using imputed whole genome sequence data on 13,715 animals. For carcass weight we found 285 SNPs in 7 QTL regions in which 54 candidate genes were identified on BTA4, BTA6 and BTA14. For back fat thickness we found 249 SNPs in 2 QTL regions containing 27 candidate genes on BTA17 and BTA19. The candidate genes from the top 5 significant SNPs were <i>ZFAT, TG</i> and <i>TOX</i> for carcass weight and <i>NOG</i> for back fat thickness. No significant SNPs for eye muscle area and marbling score were observed.</p>