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Title: Gene by Birth Type Interaction in Merino Lambs
Contributor(s): Dakhlan, A (author); Moghaddar, N  (author)orcid ; Gondro, C  (author)orcid ; van der Werf, J H J  (author)orcid 
Publication Date: 2017
Open Access: Yes
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Abstract: The purpose of this study was to investigate genome wide association of genetic markers with birth weight (BWT) and the interaction of significant marker effects with birth type (BT) in Merino lambs. Data used in this study consisted of 6,463 birth weight records of lambs generated from 349 sires and 4,896 dams of Merino sheep, which were genotyped using the Illumina Ovine SNP50 BeadChip (Illumina Inc., San Diego, CA, USA). After quality control 48,599 SNPs were included in the association study. We detected 11 and 15 genome-wide significant SNPs for birth weight in singles and twins, respectively, and 17 genome-wide significant SNPs were found when using all data. OAR6_41936490.1 and OAR6_41877997.1 were the most significant SNPs for single and twin birth weight, respectively. Among 17 significant SNPs detected by GWAS there were 9 that had a significant SNP by BT interaction, indicating that gene by BT interaction contributed to BWT variation.
Publication Type: Conference Publication
Conference Name: 22nd Association for the Advancement of Animal Breeding and Genetics (AAABG) Conference
Conference Details: Association for the Advancement of Animal Breeding and Genetics, Townsville, Queensland, Australia, 2-5 July 2017
Source of Publication: Proceedings of the Twenty-second (22nd) Conference, v.22, p. 45-48
Publisher: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Armidale, Australia
Field of Research (FOR): 070201 Animal Breeding
Socio-Economic Outcome Codes: 830310 Sheep - Meat
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
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Appears in Collections:Conference Publication
School of Environmental and Rural Science

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