Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/22986| Title: | Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry | Contributor(s): | Wilkinson, Brendan (author) ; Bornaghi, Laurent F (author); Lopez, Marie (author); Healy, Peter C (author); Poulsen, Sally-Ann (author); Houston, Todd A (author) |
Publication Date: | 2010 | DOI: | 10.1071/ch09426 | Handle Link: | https://hdl.handle.net/1959.11/22986 | Abstract: | We have developed an efficient synthesis of N-propargyl iminosugars for use in diversity-oriented library development. Through a common, crystalline intermediate both piperidine and azepane scaffolds can be prepared with an alkyne functional group, allowing for further elaboration through reaction with azides. | Publication Type: | Journal Article | Source of Publication: | Australian Journal of Chemistry, 63(5), p. 821-829 | Publisher: | CSIRO Publishing | Place of Publication: | Australia | ISSN: | 1445-0038 0004-9425 |
Fields of Research (FoR) 2008: | 030503 Organic Chemical Synthesis 030401 Biologically Active Molecules 030499 Medicinal and Biomolecular Chemistry not elsewhere classified |
Fields of Research (FoR) 2020: | 340401 Biologically active molecules 340503 Organic chemical synthesis 340499 Medicinal and biomolecular chemistry not elsewhere classified |
Socio-Economic Objective (SEO) 2008: | 970106 Expanding Knowledge in the Biological Sciences 970103 Expanding Knowledge in the Chemical Sciences 929999 Health not elsewhere classified |
Socio-Economic Objective (SEO) 2020: | 280102 Expanding knowledge in the biological sciences 200199 Clinical health not elsewhere classified 280105 Expanding knowledge in the chemical sciences |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
|---|---|
| Appears in Collections: | Journal Article School of Science and Technology |
Files in This Item:
| File | Description | Size | Format |
|---|
SCOPUSTM
Citations
12
checked on Nov 2, 2024
Page view(s)
1,390
checked on Mar 3, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.