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https://hdl.handle.net/1959.11/22924| Title: | Synthesis of MUC1-lipopeptide chimeras | Contributor(s): | Wilkinson, Brendan (author) ; Malins, Lara R (author); Chun, Candy K Y (author); Payne, Richard J (author) |
Publication Date: | 2010 | DOI: | 10.1039/c0cc01360a | Handle Link: | https://hdl.handle.net/1959.11/22924 | Abstract: | An efficient method for the convergent assembly of MUC1-lipopeptide vaccine candidates is described. Chimeras consisting of MUC1 glycopeptides (bearing multiple copies of the TN and T tumour-associated carbohydrate antigens) tethered to the lipopeptide immunoadjuvant Pam3CysSer were synthesised in high yields using a fragment-based condensation strategy. | Publication Type: | Journal Article | Source of Publication: | Chemical Communications, 46(34), p. 6249-6251 | Publisher: | Royal Society of Chemistry | Place of Publication: | United Kingdom | ISSN: | 1364-548X 1359-7345 |
Fields of Research (FoR) 2008: | 030503 Organic Chemical Synthesis 030406 Proteins and Peptides 030401 Biologically Active Molecules |
Fields of Research (FoR) 2020: | 340407 Proteins and peptides 340503 Organic chemical synthesis 340401 Biologically active molecules |
Socio-Economic Objective (SEO) 2008: | 970103 Expanding Knowledge in the Chemical Sciences 970106 Expanding Knowledge in the Biological Sciences |
Socio-Economic Objective (SEO) 2020: | 280102 Expanding knowledge in the biological sciences 280105 Expanding knowledge in the chemical sciences |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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| Appears in Collections: | Journal Article School of Science and Technology |
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