Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/22913
Title: Evidence of depression-associated circadian rhythym disruption and regret in prostate cancer patients after surgery
Contributor(s): Christie, Joanne (author); Sharpley, Christopher  (author)orcid ; Bitsika, Vicki  (author); Christie, David  (author)
Publication Date: 2017
Open Access: Yes
DOI: 10.1007/s00520-017-3913-3Open Access Link
Handle Link: https://hdl.handle.net/1959.11/22913
Abstract: Purpose The purpose of this study is to investigate the association between prostate cancer (PCa) patients' regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood, anhedonia) and a symptom of melancholic depression (disruption to circadian rhythm). Methods Forty PCa patients who had received surgery for their PCa completed a postal survey including background information, regret about surgery that 'did them a lot of harm' and three items drawn from the Zung Self-Rating Depression Scale measuring depressed mood, anhedonia and circadian rhythm disruption. Results There were significant correlations between all three symptoms of depression (depressed mood, anhedonia, disruption to circadian rhythm) and between patients' regret that surgery did them a lot of harm and their circadian rhythm disruption, but not between depressed mood or anhedonia and regret about surgery doing harm. Conclusions These findings suggest that PCa patients' postsurgery regrets about major harm may lead to a significant disruption in a central physiological function and raise the need to consider this side effect of surgery when planning supportive services for these men.
Publication Type: Journal Article
Source of Publication: Supportive Care in Cancer, 25(12), p. 3603-3605
Publisher: Springer
Place of Publication: Germany
ISSN: 0941-4355
1433-7339
Field of Research (FOR): 110903 Central Nervous System
Socio-Economic Outcome Codes: 920111 Nervous System and Disorders
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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Appears in Collections:Journal Article
School of Science and Technology

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