Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/21778
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dc.contributor.authorGodwin, Ianen
dc.contributor.authorLi, Lien
dc.contributor.authorLuijben, Ken
dc.contributor.authorOelbrandt, Nen
dc.contributor.authorVelazco, J Ien
dc.contributor.authorMiller, Jen
dc.contributor.authorHegarty, Ren
dc.date.accessioned2017-08-29T16:09:00Z
dc.date.issued2015en
dc.identifier.citationAnimal Production Science, 55(5), p. 611-616en
dc.identifier.issn1836-0939en
dc.identifier.urihttps://hdl.handle.net/1959.11/21778en
dc.description.abstractCalcium nitrate and urea were fed as a supplement on an isonitrogenous basis to Angus steers and their erythrocytic methaemoglobin concentrations and NADH- and NADPH-methaemoglobin reductase levels were measured over a 54-day period. Methaemoglobin concentrations remained elevated despite increases in NADH-methaemoglobin reductase activity. In a second experiment, Brahman cross steers were fed either calcium nitrate or urea supplements for 111 days. Blood cells were then taken, washed and exposed to sodium nitrite to convert all haemoglobin to methaemoglobin. The rates of glycolysis and methaemoglobin reduction were measured following incubation of these cells in buffers containing 1, 5 or 10 mM inorganic phosphate. Glucose consumption and methaemoglobin reduction were increased by inorganic phosphate and were more rapid in those animals supplemented with nitrate. Lactate production of erythrocytes was reduced in those animals fed nitrate. It is concluded that adaptation to chronic nitrite exposure occurs in the erythron, resulting in greater methaemoglobin reduction potential and that there is competition between NADH-methaemoglobin reductase and lactate dehydrogenase for NADH.en
dc.languageenen
dc.publisherCSIRO Publishingen
dc.relation.ispartofAnimal Production Scienceen
dc.titleThe effects of chronic nitrate supplementation on erythrocytic methaemoglobin reduction in cattleen
dc.typeJournal Articleen
dc.identifier.doi10.1071/an13366en
dc.subject.keywordsAnimal Nutritionen
dc.subject.keywordsVeterinary Medicineen
local.contributor.firstnameIanen
local.contributor.firstnameLien
local.contributor.firstnameKen
local.contributor.firstnameNen
local.contributor.firstnameJ Ien
local.contributor.firstnameJen
local.contributor.firstnameRen
local.subject.for2008070706 Veterinary Medicineen
local.subject.for2008070204 Animal Nutritionen
local.subject.seo2008960302 Climate Change Mitigation Strategiesen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.emailigodwin@une.edu.auen
local.profile.emaillli4@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20170814-181321en
local.publisher.placeClayton, Australiaen
local.format.startpage611en
local.format.endpage616en
local.peerreviewedYesen
local.identifier.volume55en
local.identifier.issue5en
local.contributor.lastnameGodwinen
local.contributor.lastnameLien
local.contributor.lastnameLuijbenen
local.contributor.lastnameOelbrandten
local.contributor.lastnameVelazcoen
local.contributor.lastnameMilleren
local.contributor.lastnameHegartyen
dc.identifier.staffune-id:igodwinen
dc.identifier.staffune-id:lli4en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:21968en
local.identifier.handlehttps://hdl.handle.net/1959.11/21778en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleThe effects of chronic nitrate supplementation on erythrocytic methaemoglobin reduction in cattleen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.description.statisticsepubsVisitors: 21<br />Views: 40<br />Downloads: 0en
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Journal Article
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