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Title: A MRI-compatible system for whisker stimulation
Contributor(s): Li, Limin (author); Weiss, Craig (author); Talk, Andrew  (author)orcid ; Disterhoft, John F (author); Wyrwicz, Alice M (author)
Publication Date: 2012
Open Access: Yes
DOI: 10.1016/j.jneumeth.2012.01.014Open Access Link
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Abstract: We describe here a system for whisker stimulation designed for functional studies in high-field magnetic resonance imaging (MRI) environments. This system, which incorporates real-time optical monitoring of the vibration stimulus, can generate well-controlled and reproducible whisker deflections with amplitudes up to 2 mm and frequencies up to 75 Hz, suitable for functional magnetic resonance imaging (fMRI) studies of animals. Whiskers on either or both sides of the head can be stimulated selectively during fMRI experiments without removing the subject from the magnet. With a user-friendly graphical interface of a computer, a user can conveniently control both the whisker vibration and gating of the MR imager, and synchronize the stimulation with the fMRI acquisition to ensure precise timing of the stimulus presentation. This whisker stimulation system should facilitate a wide variety of fMRI investigations of the neural systems mediating sensory information from the whiskers.
Publication Type: Journal Article
Source of Publication: Journal of Neuroscience Methods, 205(2), p. 305-311
Publisher: Elsevier BV
Place of Publication: The Netherlands
ISSN: 0165-0270
Field of Research (FOR): 060603 Animal Physiology - Systems
170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Socio-Economic Outcome Codes: 920111 Nervous System and Disorders
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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