Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/9264
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dc.contributor.authorAvery, Thomas Den
dc.contributor.authorMacreadie, Peter Ien
dc.contributor.authorGreatrex, Benen
dc.contributor.authorRobinson, Tony Ven
dc.contributor.authorTaylor, Dennis Ken
dc.contributor.authorMacreadie, Ian Gen
dc.date.accessioned2012-01-20T14:23:00Z-
dc.date.issued2007-
dc.identifier.citationBioorganic & Medicinal Chemistry, 15(1), p. 36-42en
dc.identifier.issn1464-3391en
dc.identifier.issn0968-0896en
dc.identifier.urihttps://hdl.handle.net/1959.11/9264-
dc.description.abstractBroad antifungal structure–activity relationships governing epoxy-endoperoxides 2 and 3 and their parent endoperoxides 1 are reported. Their inhibitory activity against 'Candida albicans' in conjunction with hemolytic activity and/or growth inhibition of cultured mammalian cells are reported. This information provided guidance for the further development of endoperoxide and epoxy-endoperoxides as topical antifungal agents.en
dc.languageenen
dc.publisherPergamon Pressen
dc.relation.ispartofBioorganic & Medicinal Chemistryen
dc.titleDesign of endoperoxides with anti-'Candida' activityen
dc.typeJournal Articleen
dc.identifier.doi10.1016/j.bmc.2006.10.021en
dc.subject.keywordsOrganic Chemical Synthesisen
dc.subject.keywordsBiologically Active Moleculesen
local.contributor.firstnameThomas Den
local.contributor.firstnamePeter Ien
local.contributor.firstnameBenen
local.contributor.firstnameTony Ven
local.contributor.firstnameDennis Ken
local.contributor.firstnameIan Gen
local.subject.for2008030503 Organic Chemical Synthesisen
local.subject.for2008030401 Biologically Active Moleculesen
local.subject.seo2008970103 Expanding Knowledge in the Chemical Sciencesen
local.subject.seo2008970106 Expanding Knowledge in the Biological Sciencesen
local.profile.schoolSchool of Rural Medicineen
local.profile.emailbgreatre@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20110325-125741en
local.publisher.placeUnited Kingdomen
local.format.startpage36en
local.format.endpage42en
local.identifier.scopusid33750964870en
local.peerreviewedYesen
local.identifier.volume15en
local.identifier.issue1en
local.contributor.lastnameAveryen
local.contributor.lastnameMacreadieen
local.contributor.lastnameGreatrexen
local.contributor.lastnameRobinsonen
local.contributor.lastnameTayloren
local.contributor.lastnameMacreadieen
dc.identifier.staffune-id:bgreatreen
local.profile.orcid0000-0002-0356-4966en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:9455en
dc.identifier.academiclevelAcademicen
local.title.maintitleDesign of endoperoxides with anti-'Candida' activityen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorAvery, Thomas Den
local.search.authorMacreadie, Peter Ien
local.search.authorGreatrex, Benen
local.search.authorRobinson, Tony Ven
local.search.authorTaylor, Dennis Ken
local.search.authorMacreadie, Ian Gen
local.uneassociationUnknownen
local.year.published2007en
Appears in Collections:Journal Article
School of Rural Medicine
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