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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/62828
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dc.contributor.authorHamilton, A Jen
dc.contributor.authorBartholomew, M Aen
dc.contributor.authorFigueroa, Jen
dc.contributor.authorFenelon, L Een
dc.contributor.authorHay, R Jen
dc.date.accessioned2024-09-14T11:52:17Z-
dc.date.available2024-09-14T11:52:17Z-
dc.identifier.citationRoyal Society of Tropical Medicine and Hygiene. Transactions, 85(1), p. 123-127en
dc.identifier.issn0035-9203en
dc.identifier.urihttps://hdl.handle.net/1959.11/62828-
dc.description.abstract<p>A panel of 4 monoclonal antibodies (mabs) of the IgGl-subclass have been made against a cytoplasmic antigen of <i>Ctyptococcus neofonnans</i>. Mab 4E2 recognized isolates of <i>C. neofmns</i> var. gatti by enzymelinked immunosorbent assav (ELISA). whilst the other antibodies did not recognize these-antigens. By Western blot 4E2 recognized determinants at llO125, 65-70. 45-50 and 36-38 kDa. Mabs 9E6. 7C7 and-5D9 recognized bands at 36-38 and approximateIv 30 kDa. All 4 mabs (4E2. 9E6. 7C7 and 5D9) recognized both non-encapsulated and encapsulated isolates of C. neoformans var. neofmns by ELISA, and in addition showed reactivity to only the cytoplasm and cell membrane of yeasts by immunofluorescence. Mab 7C7 recognized antigens of the closely related fungus <i>Trichosporon beigelii</i> by ELISA but did not recognize any other fungal antigens. The other 3 mabs showed no recognition of <i>T. beigelii</i> or any other fungal pathogens tested.</p>en
dc.languageenen
dc.publisherOxford University Pressen
dc.relation.ispartofRoyal Society of Tropical Medicine and Hygiene. Transactionsen
dc.titleMurine monoclonal antibodies recognizing a non-capsular antigen that distinguishes between Cryptococcus neoformans var. neoformans and C. neoformans var. gattiien
dc.typeJournal Articleen
dc.identifier.doi10.1016/0035-9203(91)90184-Zen
local.contributor.firstnameA Jen
local.contributor.firstnameM Aen
local.contributor.firstnameJen
local.contributor.firstnameL Een
local.contributor.firstnameR Jen
local.profile.schoolSchool of Humanities, Arts and Social Sciencesen
local.profile.emailahamil46@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeUnited Kingdomen
local.format.startpage123en
local.format.endpage127en
local.peerreviewedYesen
local.identifier.volume85en
local.identifier.issue1en
local.contributor.lastnameHamiltonen
local.contributor.lastnameBartholomewen
local.contributor.lastnameFigueroaen
local.contributor.lastnameFenelonen
local.contributor.lastnameHayen
dc.identifier.staffune-id:ahamil46en
local.profile.orcid0000-0002-4923-6335en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:1959.11/62828en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleMurine monoclonal antibodies recognizing a non-capsular antigen that distinguishes between Cryptococcus neoformans var. neoformans and C. neoformans var. gattiien
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorHamilton, A Jen
local.search.authorBartholomew, M Aen
local.search.authorFigueroa, Jen
local.search.authorFenelon, L Een
local.search.authorHay, R Jen
local.uneassociationNoen
dc.date.presented1991-
local.atsiresearchNoen
local.sensitive.culturalNoen
local.year.presented1991en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/10728020-80bd-4c43-85c2-f3906076c814en
local.subject.for20203202 Clinical sciencesen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.date.moved2024-09-17en
Appears in Collections:Journal Article
School of Humanities, Arts and Social Sciences
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