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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/62728
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dc.contributor.authorDe Luca, Mariarosariaen
dc.contributor.authorCrisci, Giuliaen
dc.contributor.authorGiardino, Federicaen
dc.contributor.authorValente, Valeriaen
dc.contributor.authorAmaranto, Ilariaen
dc.contributor.authorIacono, Olimpiaen
dc.contributor.authorD'Assante, Robertaen
dc.contributor.authorGiallauria, Francescoen
dc.contributor.authorMarra, Alberto Men
dc.date.accessioned2024-09-10T03:23:41Z-
dc.date.available2024-09-10T03:23:41Z-
dc.date.issued2022-
dc.identifier.citationMonaldi Archives for Chest Disease, 92(1), p. 1-5en
dc.identifier.issn2532-5264en
dc.identifier.issn1122-0643en
dc.identifier.urihttps://hdl.handle.net/1959.11/62728-
dc.description.abstractHeart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome that accounts for more than half of all heart failure patients. Identification, early diagnosis and management of patients are still complex, and no targeted treatment is available, since all tested drugs were not able to lower hard clinical outcomes. A multi-hormonal deficiency syndrome has been described in HFpEF patients suggesting that different hormones may represent new biomarkers of the disease, but their clinical utility is still debated. The natriuretic peptides are the cornerstone biomarker in heart failure, predicting cardiovascular death and heart failure hospitalization. Testosterone and DHEA-S deficiencies have been reported in HFpEF and associated with right ventricular impairment and diastolic dysfunction. IGFBP-1/IGF-1 axis correlates with echocardiographic parameters of HFpEF patients and with several prognostic biomarkers including NT-proBNP and C reactive protein. Low triiodothyronine syndrome is frequently found in HFpEF and thyroid hormones should represent a potential biomarker of risk stratification and prognosis.en
dc.languageenen
dc.publisherPagepressen
dc.relation.ispartofMonaldi Archives for Chest Diseaseen
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titleAnabolic hormones and heart failure with preserved ejection fraction: looking for Ariadne's threaden
dc.typeJournal Articleen
dc.identifier.doi10.4081/monaldi.2021.1743en
dc.subject.keywordsoutcomesen
dc.subject.keywordsdiagnosisen
dc.subject.keywordsheart failure preserved ejection fractionen
dc.subject.keywordsprognosisen
dc.subject.keywordsrisk stratificationen
dc.subject.keywordsRespiratory Systemen
dc.subject.keywordsAnabolic hormonesen
dc.subject.keywordsbiomarkersen
local.contributor.firstnameMariarosariaen
local.contributor.firstnameGiuliaen
local.contributor.firstnameFedericaen
local.contributor.firstnameValeriaen
local.contributor.firstnameIlariaen
local.contributor.firstnameOlimpiaen
local.contributor.firstnameRobertaen
local.contributor.firstnameFrancescoen
local.contributor.firstnameAlberto Men
local.profile.schoolSchool of Science and Technologyen
local.profile.emailfgiallau@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeItalyen
local.identifier.runningnumber1743en
local.format.startpage1en
local.format.endpage5en
local.peerreviewedYesen
local.identifier.volume92en
local.identifier.issue1en
local.title.subtitlelooking for Ariadne's threaden
local.contributor.lastnameDe Lucaen
local.contributor.lastnameCriscien
local.contributor.lastnameGiardinoen
local.contributor.lastnameValenteen
local.contributor.lastnameAmarantoen
local.contributor.lastnameIaconoen
local.contributor.lastnameD'Assanteen
local.contributor.lastnameGiallauriaen
local.contributor.lastnameMarraen
dc.identifier.staffune-id:fgiallauen
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local.identifier.unepublicationidune:1959.11/62728en
local.date.onlineversion2022-
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleAnabolic hormones and heart failure with preserved ejection fractionen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorDe Luca, Mariarosariaen
local.search.authorCrisci, Giuliaen
local.search.authorGiardino, Federicaen
local.search.authorValente, Valeriaen
local.search.authorAmaranto, Ilariaen
local.search.authorIacono, Olimpiaen
local.search.authorD'Assante, Robertaen
local.search.authorGiallauria, Francescoen
local.search.authorMarra, Alberto Men
local.uneassociationYesen
local.atsiresearchNoen
local.sensitive.culturalNoen
local.year.available2022en
local.year.published2022en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/69fb6030-989f-4616-a04c-a0d28f5a3170en
local.subject.for20203201 Cardiovascular medicine and haematologyen
local.subject.seo2020tbden
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeUNE Affiliationen
local.profile.affiliationtypeExternal Affiliationen
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School of Science and Technology
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