The relationship of food intake during growth and food intake at maturity with lactation food intake in a mouse model

Abstract

Selection for increased leanness and improved food efficiency in pigs has resulted in a decreased voluntary food intake. It has been argued that voluntary food intake during lactation should be considered in sow breeding programmes. The aim of the present study was to investigate the phenotypic correlation of food intake during growth and food intake at maturity with maximum lactation food intake in a mouse model. A total of 179 records were available on female mice selected for litter size at birth (S-line) and non-selected control females (C-line) from 3 weeks of age to 21 days in lactation. Half of the litters were standardized to eight pups per litter (s) and half were not standardized (ns). Growth intake was measured as the average intake between 21 and 42 days of age, mature intake was measured from a linear regression of food intake against age between 42 and 69 days of age, and lactation intake was measured as a linear regression of food intake against days in lactation between 5 and 14 days in lactation. In both lines, females with a higher growth intake also had a higher mature intake (r = 0.63 to 0.75, P < 0.0001). Lactation intake was related with growth intake and mature intake in Sns females (r = 0.50 and 0.46, P < 0.01) and with growth intake in Ss females (r = 0.32, P < 0.05). In both lines, lactation intake was highly correlated with litter weight (r = 0.48 to 0.94, P < 0.001). Sns and Ss females with higher growth intake supported larger litter weights during lactation (r = 0.32 and 0.30, respectively, P < 0.05) and Sns females with higher mature intakes tended to support larger litter weights (r = 0.28, P = 0.060). It is suggested that lactating C-line females eat to support a given litter size, while S-line females support the maximum litter weight that is allowed for by their intake capacity, and still produce at high levels when litters are standardized. Since lactating sows mobilise body reserves, the relationship of food intake during growth with that during lactation may be reflected in the relationship between growth intake and body condition.