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https://hdl.handle.net/1959.11/51655
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DC Field | Value | Language |
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dc.contributor.author | Peters, Ruth | en |
dc.contributor.author | Yasar, Sevil | en |
dc.contributor.author | Anderson, Craig S | en |
dc.contributor.author | Andrews, Shea | en |
dc.contributor.author | Antikainen, Riitta | en |
dc.contributor.author | Arima, Hisatomi | en |
dc.contributor.author | Beckett, Nigel | en |
dc.contributor.author | Beer, Joanne C | en |
dc.contributor.author | Bertens, Anne Suzanne | en |
dc.contributor.author | Booth, Andrew | en |
dc.contributor.author | van Boxtel, Martin | en |
dc.contributor.author | Brayne, Carol | en |
dc.contributor.author | Brodaty, Henry | en |
dc.contributor.author | Carlson, Michelle C | en |
dc.contributor.author | Chalmers, John | en |
dc.contributor.author | Corrada, Maria | en |
dc.contributor.author | DeKosky, Steven | en |
dc.contributor.author | Derby, Carol | en |
dc.contributor.author | Dixon, Roger A | en |
dc.contributor.author | Forette, Francoise | en |
dc.contributor.author | Ganguli, Mary | en |
dc.contributor.author | van Gool, Willem A | en |
dc.contributor.author | Guaita, Antonio | en |
dc.contributor.author | Hever, Ann M | en |
dc.contributor.author | Hogan, David B | en |
dc.contributor.author | Jagger, Carol | en |
dc.contributor.author | Katz, Mindy | en |
dc.contributor.author | Kawas, Claudia | en |
dc.contributor.author | Kehoe, Patrick G | en |
dc.contributor.author | Keinanen-Kiukaanniemi, Sirkka | en |
dc.contributor.author | Kenny, Rose Ann | en |
dc.contributor.author | Kohler, Sebastian | en |
dc.contributor.author | Kunutsor, Setor K | en |
dc.contributor.author | Laukkanen, Jari | en |
dc.contributor.author | Maxwell, Colleen | en |
dc.contributor.author | McFall, G Peggy | en |
dc.contributor.author | van Middelaar, Tessa | en |
dc.contributor.author | Moll van Charante, Eric P | en |
dc.contributor.author | Ng, Tze-Pin | en |
dc.contributor.author | Peters, Jean | en |
dc.contributor.author | Rawtaer, Iris | en |
dc.contributor.author | Richard, Edo | en |
dc.contributor.author | Rockwood, Kenneth | en |
dc.contributor.author | Ryden, Lina | en |
dc.contributor.author | Sachdev, Perminder S | en |
dc.contributor.author | Skoog, Ingmar | en |
dc.contributor.author | Skoog, Johan | en |
dc.contributor.author | Staessen, Jan A | en |
dc.contributor.author | Stephan, Blossom C M | en |
dc.contributor.author | Sebert, Sylvain | en |
dc.contributor.author | Thijs, Lutgarde | en |
dc.contributor.author | Trompet, Stella | en |
dc.contributor.author | Tully, Phillip J | en |
dc.contributor.author | Tzourio, Christophe | en |
dc.contributor.author | Vaccaro, Roberta | en |
dc.contributor.author | Vaaramo, Eeva | en |
dc.contributor.author | Walsh, Erin | en |
dc.contributor.author | Warwick, Jane | en |
dc.contributor.author | Anstey, Kaarin J | en |
dc.date.accessioned | 2022-04-20T04:39:56Z | - |
dc.date.available | 2022-04-20T04:39:56Z | - |
dc.date.issued | 2020-01-21 | - |
dc.identifier.citation | Neurology, 94(3), p. E267-E281 | en |
dc.identifier.issn | 1526-632X | en |
dc.identifier.issn | 0028-3878 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/51655 | - |
dc.description.abstract | <p><b>Objective</b><br/>High blood pressure is one of the main modifiable risk factors for dementia. However, there is conflicting evidence regarding the best antihypertensive class for optimizing cognition. Our objective was to determine whether any particular antihypertensive class was associated with a reduced risk of cognitive decline or dementia using comprehensive meta-analysis including reanalysis of original participant data.</br></p><p><b>Methods</b><br/>To identify suitable studies, MEDLINE, Embase, and PsycINFO and preexisting study consortia were searched from inception to December 2017. Authors of prospective longitudinal human studies or trials of antihypertensives were contacted for data sharing and collaboration. Outcome measures were incident dementia or incident cognitive decline (classified using the reliable change index method). Data were separated into mid and late-life (>65 years) and each antihypertensive class was compared to no treatment and to treatment with other antihypertensives. Meta-analysis was used to synthesize data.</br></p><p><b>Results</b><br/>Over 50,000 participants from 27 studies were included. Among those aged >65 years, with the exception of diuretics, we found no relationship by class with incident cognitive decline or dementia. Diuretic use was suggestive of benefit in some analyses but results were not consistent across follow-up time, comparator group, and outcome. Limited data precluded meaningful analyses in those ≤65 years of age.</br></p><p><b>Conclusion</b><br/>Our findings, drawn from the current evidence base, support clinical freedom in the selection of antihypertensive regimens to achieve blood pressure goals.</br></p> <p><b>Clinical trials registration</b><br/>The review was registered with the international prospective register of systematic reviews (PROSPERO), registration number CRD42016045454.</p> | en |
dc.language | en | en |
dc.publisher | Wolters Kluwer Health | en |
dc.relation.ispartof | Neurology | en |
dc.title | Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1212/WNL.0000000000008732 | en |
dc.identifier.pmid | 31827004 | en |
local.contributor.firstname | Ruth | en |
local.contributor.firstname | Sevil | en |
local.contributor.firstname | Craig S | en |
local.contributor.firstname | Shea | en |
local.contributor.firstname | Riitta | en |
local.contributor.firstname | Hisatomi | en |
local.contributor.firstname | Nigel | en |
local.contributor.firstname | Joanne C | en |
local.contributor.firstname | Anne Suzanne | en |
local.contributor.firstname | Andrew | en |
local.contributor.firstname | Martin | en |
local.contributor.firstname | Carol | en |
local.contributor.firstname | Henry | en |
local.contributor.firstname | Michelle C | en |
local.contributor.firstname | John | en |
local.contributor.firstname | Maria | en |
local.contributor.firstname | Steven | en |
local.contributor.firstname | Carol | en |
local.contributor.firstname | Roger A | en |
local.contributor.firstname | Francoise | en |
local.contributor.firstname | Mary | en |
local.contributor.firstname | Willem A | en |
local.contributor.firstname | Antonio | en |
local.contributor.firstname | Ann M | en |
local.contributor.firstname | David B | en |
local.contributor.firstname | Carol | en |
local.contributor.firstname | Mindy | en |
local.contributor.firstname | Claudia | en |
local.contributor.firstname | Patrick G | en |
local.contributor.firstname | Sirkka | en |
local.contributor.firstname | Rose Ann | en |
local.contributor.firstname | Sebastian | en |
local.contributor.firstname | Setor K | en |
local.contributor.firstname | Jari | en |
local.contributor.firstname | Colleen | en |
local.contributor.firstname | G Peggy | en |
local.contributor.firstname | Tessa | en |
local.contributor.firstname | Eric P | en |
local.contributor.firstname | Tze-Pin | en |
local.contributor.firstname | Jean | en |
local.contributor.firstname | Iris | en |
local.contributor.firstname | Edo | en |
local.contributor.firstname | Kenneth | en |
local.contributor.firstname | Lina | en |
local.contributor.firstname | Perminder S | en |
local.contributor.firstname | Ingmar | en |
local.contributor.firstname | Johan | en |
local.contributor.firstname | Jan A | en |
local.contributor.firstname | Blossom C M | en |
local.contributor.firstname | Sylvain | en |
local.contributor.firstname | Lutgarde | en |
local.contributor.firstname | Stella | en |
local.contributor.firstname | Phillip J | en |
local.contributor.firstname | Christophe | en |
local.contributor.firstname | Roberta | en |
local.contributor.firstname | Eeva | en |
local.contributor.firstname | Erin | en |
local.contributor.firstname | Jane | en |
local.contributor.firstname | Kaarin J | en |
local.profile.school | School of Psychology | en |
local.profile.email | ptully2@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.publisher.place | United States of America | en |
local.format.startpage | E267 | en |
local.format.endpage | E281 | en |
local.identifier.scopusid | 85078380895 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 94 | en |
local.identifier.issue | 3 | en |
local.title.subtitle | A meta-analysis | en |
local.contributor.lastname | Peters | en |
local.contributor.lastname | Yasar | en |
local.contributor.lastname | Anderson | en |
local.contributor.lastname | Andrews | en |
local.contributor.lastname | Antikainen | en |
local.contributor.lastname | Arima | en |
local.contributor.lastname | Beckett | en |
local.contributor.lastname | Beer | en |
local.contributor.lastname | Bertens | en |
local.contributor.lastname | Booth | en |
local.contributor.lastname | van Boxtel | en |
local.contributor.lastname | Brayne | en |
local.contributor.lastname | Brodaty | en |
local.contributor.lastname | Carlson | en |
local.contributor.lastname | Chalmers | en |
local.contributor.lastname | Corrada | en |
local.contributor.lastname | DeKosky | en |
local.contributor.lastname | Derby | en |
local.contributor.lastname | Dixon | en |
local.contributor.lastname | Forette | en |
local.contributor.lastname | Ganguli | en |
local.contributor.lastname | van Gool | en |
local.contributor.lastname | Guaita | en |
local.contributor.lastname | Hever | en |
local.contributor.lastname | Hogan | en |
local.contributor.lastname | Jagger | en |
local.contributor.lastname | Katz | en |
local.contributor.lastname | Kawas | en |
local.contributor.lastname | Kehoe | en |
local.contributor.lastname | Keinanen-Kiukaanniemi | en |
local.contributor.lastname | Kenny | en |
local.contributor.lastname | Kohler | en |
local.contributor.lastname | Kunutsor | en |
local.contributor.lastname | Laukkanen | en |
local.contributor.lastname | Maxwell | en |
local.contributor.lastname | McFall | en |
local.contributor.lastname | van Middelaar | en |
local.contributor.lastname | Moll van Charante | en |
local.contributor.lastname | Ng | en |
local.contributor.lastname | Peters | en |
local.contributor.lastname | Rawtaer | en |
local.contributor.lastname | Richard | en |
local.contributor.lastname | Rockwood | en |
local.contributor.lastname | Ryden | en |
local.contributor.lastname | Sachdev | en |
local.contributor.lastname | Skoog | en |
local.contributor.lastname | Skoog | en |
local.contributor.lastname | Staessen | en |
local.contributor.lastname | Stephan | en |
local.contributor.lastname | Sebert | en |
local.contributor.lastname | Thijs | en |
local.contributor.lastname | Trompet | en |
local.contributor.lastname | Tully | en |
local.contributor.lastname | Tzourio | en |
local.contributor.lastname | Vaccaro | en |
local.contributor.lastname | Vaaramo | en |
local.contributor.lastname | Walsh | en |
local.contributor.lastname | Warwick | en |
local.contributor.lastname | Anstey | en |
dc.identifier.staff | une-id:ptully2 | en |
local.profile.orcid | 0000-0003-2807-1313 | en |
local.profile.role | author | en |
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local.identifier.unepublicationid | une:1959.11/51655 | en |
local.date.onlineversion | 2019-12-11 | - |
dc.identifier.academiclevel | Academic | en |
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local.title.maintitle | Investigation of antihypertensive class, dementia, and cognitive decline | en |
local.relation.fundingsourcenote | The corresponding author is funded by the Australian National Health and Medical Research Council, National Institute for Dementia Research, and Dementia Centre for Research Collaboration (NHMRC NNIDR DCRC). | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Peters, Ruth | en |
local.search.author | Yasar, Sevil | en |
local.search.author | Anderson, Craig S | en |
local.search.author | Andrews, Shea | en |
local.search.author | Antikainen, Riitta | en |
local.search.author | Arima, Hisatomi | en |
local.search.author | Beckett, Nigel | en |
local.search.author | Beer, Joanne C | en |
local.search.author | Bertens, Anne Suzanne | en |
local.search.author | Booth, Andrew | en |
local.search.author | van Boxtel, Martin | en |
local.search.author | Brayne, Carol | en |
local.search.author | Brodaty, Henry | en |
local.search.author | Carlson, Michelle C | en |
local.search.author | Chalmers, John | en |
local.search.author | Corrada, Maria | en |
local.search.author | DeKosky, Steven | en |
local.search.author | Derby, Carol | en |
local.search.author | Dixon, Roger A | en |
local.search.author | Forette, Francoise | en |
local.search.author | Ganguli, Mary | en |
local.search.author | van Gool, Willem A | en |
local.search.author | Guaita, Antonio | en |
local.search.author | Hever, Ann M | en |
local.search.author | Hogan, David B | en |
local.search.author | Jagger, Carol | en |
local.search.author | Katz, Mindy | en |
local.search.author | Kawas, Claudia | en |
local.search.author | Kehoe, Patrick G | en |
local.search.author | Keinanen-Kiukaanniemi, Sirkka | en |
local.search.author | Kenny, Rose Ann | en |
local.search.author | Kohler, Sebastian | en |
local.search.author | Kunutsor, Setor K | en |
local.search.author | Laukkanen, Jari | en |
local.search.author | Maxwell, Colleen | en |
local.search.author | McFall, G Peggy | en |
local.search.author | van Middelaar, Tessa | en |
local.search.author | Moll van Charante, Eric P | en |
local.search.author | Ng, Tze-Pin | en |
local.search.author | Peters, Jean | en |
local.search.author | Rawtaer, Iris | en |
local.search.author | Richard, Edo | en |
local.search.author | Rockwood, Kenneth | en |
local.search.author | Ryden, Lina | en |
local.search.author | Sachdev, Perminder S | en |
local.search.author | Skoog, Ingmar | en |
local.search.author | Skoog, Johan | en |
local.search.author | Staessen, Jan A | en |
local.search.author | Stephan, Blossom C M | en |
local.search.author | Sebert, Sylvain | en |
local.search.author | Thijs, Lutgarde | en |
local.search.author | Trompet, Stella | en |
local.search.author | Tully, Phillip J | en |
local.search.author | Tzourio, Christophe | en |
local.search.author | Vaccaro, Roberta | en |
local.search.author | Vaaramo, Eeva | en |
local.search.author | Walsh, Erin | en |
local.search.author | Warwick, Jane | en |
local.search.author | Anstey, Kaarin J | en |
local.uneassociation | No | en |
local.atsiresearch | No | en |
local.sensitive.cultural | No | en |
local.identifier.wosid | 000530131000010 | en |
local.year.available | 2019 | en |
local.year.published | 2020 | en |
local.fileurl.closedpublished | https://rune.une.edu.au/web/retrieve/763636dc-7843-42c5-b0ae-a176340631d7 | en |
local.subject.for2020 | 520304 Health psychology | en |
local.subject.for2020 | 520302 Clinical psychology | en |
local.subject.seo2020 | 200502 Health related to ageing | en |
local.subject.seo2020 | 200409 Mental health | en |
Appears in Collections: | Journal Article School of Psychology |
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