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https://hdl.handle.net/1959.11/51496
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DC Field | Value | Language |
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dc.contributor.author | Thomas, Frédéric | en |
dc.contributor.author | Giraudeau, Mathieu | en |
dc.contributor.author | Dheilly, Nolwenn M | en |
dc.contributor.author | Gouzerh, Flora | en |
dc.contributor.author | Boutry, Justine | en |
dc.contributor.author | Beckmann, Christa | en |
dc.contributor.author | Biro, Peter A | en |
dc.contributor.author | Hamede, Rodrigo | en |
dc.contributor.author | Abadie, Jerome | en |
dc.contributor.author | Labrut, Sophie | en |
dc.contributor.author | Bieuville, Margaux | en |
dc.contributor.author | Misse, Dorothée | en |
dc.contributor.author | Bramwell, Georgina | en |
dc.contributor.author | Schultz, Aaron | en |
dc.contributor.author | Le Loc'h, Guillaume | en |
dc.contributor.author | Vincze, Orsolya | en |
dc.contributor.author | Roche, Benjamin | en |
dc.contributor.author | Renaud, François | en |
dc.contributor.author | Russell, Tracey | en |
dc.contributor.author | Ujvari, Beata | en |
dc.date.accessioned | 2022-03-31T00:03:58Z | - |
dc.date.available | 2022-03-31T00:03:58Z | - |
dc.date.issued | 2020-08 | - |
dc.identifier.citation | Evolutionary Applications, 13(7), p. 1605-1614 | en |
dc.identifier.issn | 1752-4571 | en |
dc.identifier.issn | 1752-4563 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/51496 | - |
dc.description.abstract | <p>Strong and ongoing artificial selection in domestic animals has resulted in amazing phenotypic responses that benefit humans, but often at a cost to an animal's health, and problems related to inbreeding depression, including a higher incidence of cancer. Despite high rates of cancer in domesticated species, little attention has been devoted to exploring the hypothesis that persistent artificial selection may also favour the evolution of compensatory anticancer defences. Indeed, there is evidence for effective anti-cancer defences found in several domesticated species associated with different cancer types. We also suggest that artificial selection can favour the "domestication" of inherited oncogenic mutations in rare instances, retaining those associated to late and/or less aggressive cancers, and that by studying these seemingly rare anticancer adaptations, novel cancer treatments may be found.</p> | en |
dc.language | en | en |
dc.publisher | Wiley-Blackwell Publishing, Inc | en |
dc.relation.ispartof | Evolutionary Applications | en |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | Rare and unique adaptations to cancer in domesticated species: An untapped resource? | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1111/eva.12920 | en |
dcterms.accessRights | UNE Green | en |
local.contributor.firstname | Frédéric | en |
local.contributor.firstname | Mathieu | en |
local.contributor.firstname | Nolwenn M | en |
local.contributor.firstname | Flora | en |
local.contributor.firstname | Justine | en |
local.contributor.firstname | Christa | en |
local.contributor.firstname | Peter A | en |
local.contributor.firstname | Rodrigo | en |
local.contributor.firstname | Jerome | en |
local.contributor.firstname | Sophie | en |
local.contributor.firstname | Margaux | en |
local.contributor.firstname | Dorothée | en |
local.contributor.firstname | Georgina | en |
local.contributor.firstname | Aaron | en |
local.contributor.firstname | Guillaume | en |
local.contributor.firstname | Orsolya | en |
local.contributor.firstname | Benjamin | en |
local.contributor.firstname | François | en |
local.contributor.firstname | Tracey | en |
local.contributor.firstname | Beata | en |
local.relation.isfundedby | ARC | en |
local.profile.school | School of Environmental and Rural Science | en |
local.profile.email | cbeckman@une.edu.au | en |
local.output.category | C1 | en |
local.grant.number | LP170101105 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.publisher.place | United States of America | en |
local.format.startpage | 1605 | en |
local.format.endpage | 1614 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 13 | en |
local.identifier.issue | 7 | en |
local.title.subtitle | An untapped resource? | en |
local.access.fulltext | Yes | en |
local.contributor.lastname | Thomas | en |
local.contributor.lastname | Giraudeau | en |
local.contributor.lastname | Dheilly | en |
local.contributor.lastname | Gouzerh | en |
local.contributor.lastname | Boutry | en |
local.contributor.lastname | Beckmann | en |
local.contributor.lastname | Biro | en |
local.contributor.lastname | Hamede | en |
local.contributor.lastname | Abadie | en |
local.contributor.lastname | Labrut | en |
local.contributor.lastname | Bieuville | en |
local.contributor.lastname | Misse | en |
local.contributor.lastname | Bramwell | en |
local.contributor.lastname | Schultz | en |
local.contributor.lastname | Le Loc'h | en |
local.contributor.lastname | Vincze | en |
local.contributor.lastname | Roche | en |
local.contributor.lastname | Renaud | en |
local.contributor.lastname | Russell | en |
local.contributor.lastname | Ujvari | en |
dc.identifier.staff | une-id:cbeckman | en |
local.profile.orcid | 0000-0002-7904-7228 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:1959.11/51496 | en |
local.date.onlineversion | 2020-01-20 | - |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Rare and unique adaptations to cancer in domesticated species | en |
local.relation.fundingsourcenote | Deakin SEBE_RGS_2019; ANR TRANSCAN, Grant/Award Number: ANR-18-CE35-0009; CNRS 'International Associated Laboratory Grant'; The Rotary Club Les Sables d'Olonne; The Romanian Ministry of Research and Innovation, Grant/Award Number: PN-III-P4-ID-PCE-2016-0404; The János Bolyai Research Scholarship of the Hungarian Academy of Sciences; The New National Excellence Program of the Ministry of Innovation and Technology, Grant/Award Number: ÚNKP-19-4-DE-538. | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.relation.grantdescription | ARC/LP170101105 | en |
local.search.author | Thomas, Frédéric | en |
local.search.author | Giraudeau, Mathieu | en |
local.search.author | Dheilly, Nolwenn M | en |
local.search.author | Gouzerh, Flora | en |
local.search.author | Boutry, Justine | en |
local.search.author | Beckmann, Christa | en |
local.search.author | Biro, Peter A | en |
local.search.author | Hamede, Rodrigo | en |
local.search.author | Abadie, Jerome | en |
local.search.author | Labrut, Sophie | en |
local.search.author | Bieuville, Margaux | en |
local.search.author | Misse, Dorothée | en |
local.search.author | Bramwell, Georgina | en |
local.search.author | Schultz, Aaron | en |
local.search.author | Le Loc'h, Guillaume | en |
local.search.author | Vincze, Orsolya | en |
local.search.author | Roche, Benjamin | en |
local.search.author | Renaud, François | en |
local.search.author | Russell, Tracey | en |
local.search.author | Ujvari, Beata | en |
local.open.fileurl | https://rune.une.edu.au/web/retrieve/f0820db9-fac1-4b53-a8e4-95518826e763 | en |
local.uneassociation | No | en |
local.atsiresearch | No | en |
local.sensitive.cultural | No | en |
local.year.available | 2020 | en |
local.year.published | 2020 | en |
local.fileurl.open | https://rune.une.edu.au/web/retrieve/f0820db9-fac1-4b53-a8e4-95518826e763 | en |
local.fileurl.openpublished | https://rune.une.edu.au/web/retrieve/f0820db9-fac1-4b53-a8e4-95518826e763 | en |
local.subject.for2020 | 310914 Vertebrate biology | en |
local.subject.seo2020 | 180606 Terrestrial biodiversity | en |
Appears in Collections: | Journal Article School of Environmental and Rural Science |
Files in This Item:
File | Description | Size | Format | |
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openpublished/RareBeckmann2020JournalArticle.pdf | Published version | 476.2 kB | Adobe PDF Download Adobe | View/Open |
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