Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/47820
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DC Field | Value | Language |
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dc.contributor.author | Haynes, Andrew | en |
dc.contributor.author | Linden, Matthew D | en |
dc.contributor.author | Robey, Elisa | en |
dc.contributor.author | Watts, Gerald F | en |
dc.contributor.author | Barrett, P Hugh R | en |
dc.contributor.author | Naylor, Louise H | en |
dc.contributor.author | Green, Daniel J | en |
dc.date.accessioned | 2022-03-08T02:10:05Z | - |
dc.date.available | 2022-03-08T02:10:05Z | - |
dc.date.issued | 2018-04 | - |
dc.identifier.citation | Medicine and Science in Sports and Exercise, 50(4), p. 785-791 | en |
dc.identifier.issn | 1530-0315 | en |
dc.identifier.issn | 0195-9131 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/47820 | - |
dc.description.abstract | <p><b>Purpose</b>: Acute coronary syndromes and ischemic stroke are associated with arterial events involving platelets, the endothelium, and atherosclerosis. Although regular physical activity is associated with lower risk of cardiovascular events and mortality, risk is transiently increased during and immediately after participation in an acute bout of exercise. No previous study has investigated the acute impact of exercise on platelet activation and arterial function in the same participants; it is also unknown if responses are dependent on exercise modality. We hypothesized that commonly adopted, yet physiologically distinct, modalities of exercise ("aerobic" vs "resistance") have differing effects on <i>in vivo</i> platelet activation and conduit artery diameter. <b>Methods</b>: Eight apparently healthy middle-age (53.5 ± 1.6 yr) male subjects took part in four 30-min experimental interventions (aerobic exercise, resistance exercise, combined aerobic/resistance exercise, or no-exercise), in random order. Blood samples were collected, and the measurement of brachial artery diameter by ultrasound was performed before, immediately after, and 1 h after each intervention. Platelet activation was determined by the positive binding of antibodies to surface receptors exposed on activated platelets (anti-CD62P and PAC-1). <b>Results</b>: Brachial artery diameter increased immediately after all three exercise modalities (<i>P</i> < 0.001) and remained above preexercise levels 1 h after resistance exercise and after combined aerobic/resistance exercise. No changes were observed in markers of <i>in vivo</i> platelet activation with any experimental protocol. <b>Conclusions</b>: These data suggest that postexercise enhancement in arterial function may mitigate the acute impact of exercise on platelet activation.</p> | en |
dc.language | en | en |
dc.publisher | Lippincott Williams & Wilkins | en |
dc.relation.ispartof | Medicine and Science in Sports and Exercise | en |
dc.title | Acute Impact of Different Exercise Modalities on Arterial and Platelet Function | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1249/MSS.0000000000001505 | en |
local.contributor.firstname | Andrew | en |
local.contributor.firstname | Matthew D | en |
local.contributor.firstname | Elisa | en |
local.contributor.firstname | Gerald F | en |
local.contributor.firstname | P Hugh R | en |
local.contributor.firstname | Louise H | en |
local.contributor.firstname | Daniel J | en |
local.relation.isfundedby | NHMRC | en |
local.profile.school | Faculty of Medicine and Health | en |
local.profile.email | pbarret6@une.edu.au | en |
local.output.category | C1 | en |
local.grant.number | APP1080914 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.publisher.place | United States of America | en |
local.format.startpage | 785 | en |
local.format.endpage | 791 | en |
local.identifier.scopusid | 85044065267 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 50 | en |
local.identifier.issue | 4 | en |
local.contributor.lastname | Haynes | en |
local.contributor.lastname | Linden | en |
local.contributor.lastname | Robey | en |
local.contributor.lastname | Watts | en |
local.contributor.lastname | Barrett | en |
local.contributor.lastname | Naylor | en |
local.contributor.lastname | Green | en |
dc.identifier.staff | une-id:pbarret6 | en |
local.profile.orcid | 0000-0003-3223-6125 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:1959.11/47820 | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Acute Impact of Different Exercise Modalities on Arterial and Platelet Function | en |
local.relation.fundingsourcenote | National Heart Foundation of Australia (G12P6417) | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.relation.grantdescription | NHMRC/APP1080914 | en |
local.search.author | Haynes, Andrew | en |
local.search.author | Linden, Matthew D | en |
local.search.author | Robey, Elisa | en |
local.search.author | Watts, Gerald F | en |
local.search.author | Barrett, P Hugh R | en |
local.search.author | Naylor, Louise H | en |
local.search.author | Green, Daniel J | en |
local.uneassociation | No | en |
local.atsiresearch | No | en |
local.sensitive.cultural | No | en |
local.identifier.wosid | 000427796400019 | en |
local.year.published | 2018 | en |
local.fileurl.closedpublished | https://rune.une.edu.au/web/retrieve/bb5dffc9-6d97-478d-a62d-502dc500eeb1 | en |
local.subject.for2020 | 320101 Cardiology (incl. cardiovascular diseases) | en |
local.subject.seo2020 | 200105 Treatment of human diseases and conditions | en |
Appears in Collections: | Journal Article School of Science and Technology |
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