Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/29502
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DC Field | Value | Language |
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dc.contributor.author | Taylor, Rod S | en |
dc.contributor.author | Walker, Sarah | en |
dc.contributor.author | Smart, Neil A | en |
dc.contributor.author | Piepoli, Massimo F | en |
dc.contributor.author | Warren, Fiona C | en |
dc.contributor.author | Ciani, Oriana | en |
dc.contributor.author | Whellan, David | en |
dc.contributor.author | O'Connor, Christopher | en |
dc.contributor.author | Keteyian, Steven J | en |
dc.contributor.author | Coats, Andrew | en |
dc.contributor.author | Davos, Constantinos H | en |
dc.contributor.author | Dalal, Hasnain M | en |
dc.contributor.author | Dracup, Kathleen | en |
dc.contributor.author | Evangelista, Lorraine S | en |
dc.contributor.author | Jolly, Kate | en |
dc.contributor.author | Myers, Jonathan | en |
dc.contributor.author | Nilsson, Birgitta B | en |
dc.contributor.author | Passino, Claudio | en |
dc.contributor.author | Witham, Miles D | en |
dc.contributor.author | Yeh, Gloria Y | en |
dc.date.accessioned | 2020-10-02T05:35:31Z | - |
dc.date.available | 2020-10-02T05:35:31Z | - |
dc.date.issued | 2019-04-02 | - |
dc.identifier.citation | Journal of the American College of Cardiology, 73(12), p. 1430-1443 | en |
dc.identifier.issn | 1558-3597 | en |
dc.identifier.issn | 0735-1097 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/29502 | - |
dc.description.abstract | <b>Background</b> Previous systematic reviews have indicated that exercise-based cardiac rehabilitation (ExCR) for patients with heart failure (HF) has a beneficial effect on health-related quality-of-life (HRQoL) and exercise capacity. However, there is uncertainty regarding potential differential effects of ExCR across HF patient subgroups.<br/><b>Objectives</b> The authors sought to undertake an individual participant data (IPD) meta-analysis to: 1) assess the impact of ExCR on HRQoL and exercise capacity in patients with HF; and 2) investigate differential effects of ExCR according to a range of patient characteristics: age, sex, ethnicity, New York Heart Association functional class, ischemic etiology, ejection fraction, and exercise capacity.<br/><b>Methods</b> A single dataset was produced, comprising randomized trials where ExCR (delivered for 3 weeks or more) was compared with a no exercise control group. Each trial provided IPD on HRQoL or exercise capacity (or both), with follow-up of 6 months or more. One- and 2-stage meta-analysis models were used to investigate the effect of ExCR overall and the interactions between ExCR and participant characteristics.<br/><b>Results</b> IPD was obtained from 13 trials for 3,990 patients, predominantly (97%) with reduced ejection fraction HF. Compared with the control group, there was a statistically significant difference in favor of ExCR for HRQoL and exercise capacity. At 12-month follow-up, improvements were seen in 6-min walk test (mean 21.0 m; 95% confidence interval: 1.57 to 40.4 m; p = 0.034) and Minnesota Living With HF score (mean improvement 5.9; 95% confidence interval: 1.0 to 10.9; p = 0.018). No consistent evidence was found of differential intervention effects across patient subgroups.<br/><b>Conclusions</b> These results, based on an IPD meta-analysis of randomized trials, confirm the benefit of ExCR on HRQoL and exercise capacity and support the Class I recommendation of current international clinical guidelines that ExCR should be offered to all HF patients. (Exercise Training for Chronic Heart Failure [ExTraMATCH II]: protocol for an individual participant data meta-analysis; PROSPERO: international database of systematic reviews CRD42014007170) | en |
dc.language | en | en |
dc.publisher | Elsevier Inc | en |
dc.relation.ispartof | Journal of the American College of Cardiology | en |
dc.title | Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure Individual Participant Meta-Analysis | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1016/j.jacc.2018.12.072 | en |
dc.identifier.pmid | 30922474 | en |
dcterms.accessRights | Gold | en |
local.contributor.firstname | Rod S | en |
local.contributor.firstname | Sarah | en |
local.contributor.firstname | Neil A | en |
local.contributor.firstname | Massimo F | en |
local.contributor.firstname | Fiona C | en |
local.contributor.firstname | Oriana | en |
local.contributor.firstname | David | en |
local.contributor.firstname | Christopher | en |
local.contributor.firstname | Steven J | en |
local.contributor.firstname | Andrew | en |
local.contributor.firstname | Constantinos H | en |
local.contributor.firstname | Hasnain M | en |
local.contributor.firstname | Kathleen | en |
local.contributor.firstname | Lorraine S | en |
local.contributor.firstname | Kate | en |
local.contributor.firstname | Jonathan | en |
local.contributor.firstname | Birgitta B | en |
local.contributor.firstname | Claudio | en |
local.contributor.firstname | Miles D | en |
local.contributor.firstname | Gloria Y | en |
local.subject.for2008 | 110201 Cardiology (incl. Cardiovascular Diseases) | en |
local.subject.seo2008 | 920412 Preventive Medicine | en |
local.profile.school | School of Science and Technology | en |
local.profile.email | nsmart2@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.publisher.place | United States of America | en |
local.format.startpage | 1430 | en |
local.format.endpage | 1443 | en |
local.identifier.scopusid | 85062963920 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 73 | en |
local.identifier.issue | 12 | en |
local.access.fulltext | Yes | en |
local.contributor.lastname | Taylor | en |
local.contributor.lastname | Walker | en |
local.contributor.lastname | Smart | en |
local.contributor.lastname | Piepoli | en |
local.contributor.lastname | Warren | en |
local.contributor.lastname | Ciani | en |
local.contributor.lastname | Whellan | en |
local.contributor.lastname | O'Connor | en |
local.contributor.lastname | Keteyian | en |
local.contributor.lastname | Coats | en |
local.contributor.lastname | Davos | en |
local.contributor.lastname | Dalal | en |
local.contributor.lastname | Dracup | en |
local.contributor.lastname | Evangelista | en |
local.contributor.lastname | Jolly | en |
local.contributor.lastname | Myers | en |
local.contributor.lastname | Nilsson | en |
local.contributor.lastname | Passino | en |
local.contributor.lastname | Witham | en |
local.contributor.lastname | Yeh | en |
dc.identifier.staff | une-id:nsmart2 | en |
local.profile.orcid | 0000-0002-8290-6409 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:1959.11/29502 | en |
local.date.onlineversion | 2019-03-25 | - |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure Individual Participant Meta-Analysis | en |
local.relation.fundingsourcenote | National Institute for Health Research Health Technology Assessment Programme (NIHR-HTA 15/80/30) | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Taylor, Rod S | en |
local.search.author | Walker, Sarah | en |
local.search.author | Smart, Neil A | en |
local.search.author | Piepoli, Massimo F | en |
local.search.author | Warren, Fiona C | en |
local.search.author | Ciani, Oriana | en |
local.search.author | Whellan, David | en |
local.search.author | O'Connor, Christopher | en |
local.search.author | Keteyian, Steven J | en |
local.search.author | Coats, Andrew | en |
local.search.author | Davos, Constantinos H | en |
local.search.author | Dalal, Hasnain M | en |
local.search.author | Dracup, Kathleen | en |
local.search.author | Evangelista, Lorraine S | en |
local.search.author | Jolly, Kate | en |
local.search.author | Myers, Jonathan | en |
local.search.author | Nilsson, Birgitta B | en |
local.search.author | Passino, Claudio | en |
local.search.author | Witham, Miles D | en |
local.search.author | Yeh, Gloria Y | en |
local.uneassociation | Yes | en |
local.atsiresearch | No | en |
local.sensitive.cultural | No | en |
local.identifier.wosid | 000462141600010 | en |
local.year.available | 2019 | en |
local.year.published | 2019 | en |
local.fileurl.closedpublished | https://rune.une.edu.au/web/retrieve/4877941b-9a5e-46eb-b8ff-9de2763d61f8 | en |
local.subject.for2020 | 320101 Cardiology (incl. cardiovascular diseases) | en |
local.subject.seo2020 | 200412 Preventive medicine | en |
Appears in Collections: | Journal Article School of Science and Technology |
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