Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/29305
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DC Field | Value | Language |
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dc.contributor.author | Van Der Touw, Tom | en |
dc.contributor.author | Andronicos, Nicholas Matthew | en |
dc.contributor.author | Smart, Neil | en |
dc.date.accessioned | 2020-08-26T05:05:16Z | - |
dc.date.available | 2020-08-26T05:05:16Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Biomarkers, 24(5), p. 429-435 | en |
dc.identifier.issn | 1366-5804 | en |
dc.identifier.issn | 1354-750X | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/29305 | - |
dc.description.abstract | <p><b>Purpose:</b> This study examined whether circulating C-reactive protein (CRP) is elevated in obstructive sleep apnoea (OSA) independent of the confounding effects of comorbidities, smoking, body mass index (BMI), age and gender.</p><p><b>Methods:</b> A systematic review of the literature was performed using PubMed, Embase and Cochrane databases from 1 January 1997 to 1 November 2017 using the key words obstructive sleep apnoea and C-Reactive protein to identify full text English language studies that compared CRP in adult non-smoking OSA participants without comorbidities and adult healthy non-smoking control participants matched for BMI, age and gender. Data from eligible studies were subjected to meta-analysis using RevMan version 5.3.</p><p><b>Results:</b> Five studies (219 OSA participants, 116 controls) met the selection criteria. The total standard mean difference for circulating high sensitivity CRP was 0.61 mg/dL higher in OSA participants than in control participants (confidence interval: 0.38 to 0.84, <i>p</i> < 0.00001), with low between-studies heterogeneity (df = 7, <i>p</i> = 0.16, <i>I<sup>2</sup></i> = 33%) and minimal evidence of publication bias.</p><p><b>Conclusions:</b> CRP levels in non-smoking OSA participants without comorbidities were increased relative to levels in healthy matched non-smoking control participants, suggesting that pharyngeal or systemic inflammatory effects attributable to OSA may elevate CRP.</p> | en |
dc.language | en | en |
dc.publisher | Taylor & Francis | en |
dc.relation.ispartof | Biomarkers | en |
dc.title | Is C-reactive protein elevated in obstructive sleep apnea? a systematic review and meta-analysis | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1080/1354750X.2019.1600025 | en |
dc.identifier.pmid | 30908094 | en |
local.contributor.firstname | Tom | en |
local.contributor.firstname | Nicholas Matthew | en |
local.contributor.firstname | Neil | en |
local.subject.for2008 | 110203 Respiratory Diseases | en |
local.subject.seo2008 | 920115 Respiratory System and Diseases (incl. Asthma) | en |
local.profile.school | School of Science and Technology | en |
local.profile.school | School of Science and Technology | en |
local.profile.school | School of Science and Technology | en |
local.profile.email | tvandert@une.edu.au | en |
local.profile.email | nandroni@une.edu.au | en |
local.profile.email | nsmart2@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.publisher.place | United Kingdom | en |
local.format.startpage | 429 | en |
local.format.endpage | 435 | en |
local.identifier.scopusid | 85064595468 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 24 | en |
local.identifier.issue | 5 | en |
local.contributor.lastname | Van Der Touw | en |
local.contributor.lastname | Andronicos | en |
local.contributor.lastname | Smart | en |
dc.identifier.staff | une-id:tvandert | en |
dc.identifier.staff | une-id:nandroni | en |
dc.identifier.staff | une-id:nsmart2 | en |
local.profile.orcid | 0000-0001-5881-2296 | en |
local.profile.orcid | 0000-0002-8290-6409 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:1959.11/29305 | en |
local.date.onlineversion | 2019-04-17 | - |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Is C-reactive protein elevated in obstructive sleep apnea? a systematic review and meta-analysis | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Van Der Touw, Tom | en |
local.search.author | Andronicos, Nicholas Matthew | en |
local.search.author | Smart, Neil | en |
local.uneassociation | Yes | en |
local.atsiresearch | No | en |
local.sensitive.cultural | No | en |
local.year.available | 2019 | en |
local.year.published | 2019 | en |
local.fileurl.closedpublished | https://rune.une.edu.au/web/retrieve/8c5ca065-9338-41a4-b2a9-21359d0affc0 | en |
local.subject.for2020 | 320803 Systems physiology | en |
local.subject.for2020 | 320101 Cardiology (incl. cardiovascular diseases) | en |
local.subject.seo2020 | 200104 Prevention of human diseases and conditions | en |
local.codeupdate.date | 2021-10-31T11:38:38.863 | en |
local.codeupdate.eperson | nandroni@une.edu.au | en |
local.codeupdate.finalised | true | en |
local.original.for2020 | 320103 Respiratory diseases | en |
local.original.seo2020 | undefined | en |
Appears in Collections: | Journal Article School of Science and Technology |
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