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https://hdl.handle.net/1959.11/28728
Title: | Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds | Contributor(s): | Heffernan, Megan (author); Andrews, Gavin (author); Fiatarone Singh, Maria A (author); Valenzuela, Michael (author); Anstey, Kaarin J (author); Maeder, Anthony J (author); McNeil, John (author); Jorm, Louisa (author); Lautenschlager, Nicola T (author); Sachdev, Perminder S (author); Ginige, Jeewani A (author); Hobbs, Megan J (author) ; Boulamatsis, Christos (author); Chau, Tiffany (author); Cobiac, Lynne (author); Cox, Kay L (author); Daniel, Kenneth (author); Flood, Victoria M (author); Guerrero, Yareni (author); Gunn, Jane (author); Jain, Nidhi (author); Kochan, Nicole A (author); Lampit, Amit (author); Mavros, Yorgi (author); Meiklejohn, Jacinda (author); Noble, Yian (author); O'Leary, Fiona (author); Radd-Vagenas, Sue (author); Walton, Courtney C (author); Bosler, Nan (author); Betz-Stablein, Brigid (author); Briggs, Nancy (author); Christensen, Helen (author); Chuprov, Igor (author); Hayen, Andrew (author); Kivipelto, Miia (author); Lapsley, Helen (author); Redman, Sally (author); San Jose, Juan Carlo (author); Welberry, Heidi (author); Brodaty, Henry (author) | Corporate Author: | Maintain Your Brain Collaborative Team | Publication Date: | 2019-08-13 | Open Access: | Yes | DOI: | 10.3233/JAD-180572 | Handle Link: | https://hdl.handle.net/1959.11/28728 | Abstract: | Background: Maintain Your Brain (MYB) is a randomized controlled trial of an online multi-modal lifestyle intervention targeting modifiable dementia risk factors with its primary aim being to reduce cognitive decline in an older age cohort. Methods: MYB aims to recruit 8,500 non-demented community dwelling 55 to 77 year olds from the Sax Institute’s 45 and Up Study in New South Wales, Australia. Participants will be screened for risk factors related to four modules that comprise the MYB intervention: physical activity, nutrition, mental health, and cognitive training. Targeting risk factors will enable interventions to be personalized so that participants receive the most appropriate modules. MYB will run for three years and up to four modules will be delivered sequentially each quarter during year one. Upon completing a module, participants will continue to receive less frequent booster activities for their eligible modules (except for the mental health module) until the end of the trial. Discussion: MYB will be the largest internet-based trial to attempt to prevent cognitive decline and potentially dementia. If successful, MYB will provide a model for not just effective intervention among older adults, but an intervention that is scalable for broad use. | Publication Type: | Journal Article | Grant Details: | NHMRC/1095097 NHMRC/1112813 |
Source of Publication: | Journal of Alzheimer's Disease, 70(s1), p. S221-S237 | Publisher: | IOS Press | Place of Publication: | Netherlands | ISSN: | 1875-8908 1387-2877 |
Fields of Research (FoR) 2008: | 110319 Psychiatry (incl. Psychotherapy) 111714 Mental Health 170102 Developmental Psychology and Ageing |
Fields of Research (FoR) 2020: | 320221 Psychiatry (incl. psychotherapy) 520106 Psychology of ageing |
Socio-Economic Objective (SEO) 2008: | 920112 Neurodegenerative Disorders Related to Ageing 920410 Mental Health 920204 Evaluation of Health Outcomes |
Socio-Economic Objective (SEO) 2020: | 200202 Evaluation of health outcomes 200409 Mental health |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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