Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/27743
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGharib-Naseri, Ken
dc.contributor.authorKheravii, S Ken
dc.contributor.authorKeerqin, Cen
dc.contributor.authorMorgan, Nen
dc.contributor.authorSwick, R Aen
dc.contributor.authorChoct, Men
dc.contributor.authorWu, S-Ben
dc.date.accessioned2019-11-08T05:07:10Z-
dc.date.available2019-11-08T05:07:10Zen
dc.date.issued2019-12-
dc.identifier.citationPoultry Science, 98(12), p. 6422-6432en
dc.identifier.issn1525-3171en
dc.identifier.issn0032-5791en
dc.identifier.urihttps://hdl.handle.net/1959.11/27743-
dc.description.abstractSubclinical necrotic enteritis (NE) is primarily caused by the gram-positive bacterium, Clostridium perfringens (Cp). The trend towards removal of in-feed antimicrobials and subsequent increased emergence of infection in poultry has resulted in a wide interest in better understanding of the mechanism behind this disease. The virulence of NE, to a large extent, depends on the virulence of Cp strains. Thus, this study was to assess how 2 different strains of Cp affect performance and gut characteristics of broiler chickens. Ross 308 male broilers (n = 468) were assigned to a 2 × 3 factorial arrangement of treatments with antibiotics (Salinomycin at 72 ppm and zinc bacitracin at 50 ppm −, or +) and challenge (non-challenge, Cp EHE-NE18, or Cp WER-NE36). Oral administration of Eimeria oocysts (day 9) followed by inoculation with 1 mL 108 CFU Cp strains (day 14 and 15) were used to induce NE. Broiler performance was analyzed at day 10, 24, and 35. On day 16, intestinal lesion score and intestinal pH were evaluated and samples of cecal content were analyzed for bacterial counts and short-chain fatty acid concentrations (SCFA). Birds in both challenged groups showed higher feed conversion ratio (FCR), lower weight gain (P < 0.001), increased lesion scores in the jejunum (P < 0.01), and reduced pH in the ileum and cecum (P < 0.01), compared to the non-challenged birds. They also showed decreased numbers of Bacillus spp. (P < 0.001), and Ruminococcus spp. (P < 0.01) in the cecal content. On day 35, the NE36 challenged birds had a lower weight gain (P < 0.001) and higher FCR (P < 0.001) compared to the NE18 challenged birds. Interestingly, cecal Lactobacillus and lactate were increased by the NE challenge (P < 0.001), and to a greater extent in birds challenged with NE36 compared to the NE18 strain (P < 0.001). This study suggests that Cp strains varying in virulence produce different levels of disease in broiler chickens through modulating the gut environment, intestinal microbiota, and SCFA profile to different extents.en
dc.languageenen
dc.publisherOxford University Pressen
dc.relation.ispartofPoultry Scienceen
dc.titleTwo different Clostridium perfringens strains produce different levels of necrotic enteritis in broiler chickensen
dc.typeJournal Articleen
dc.identifier.doi10.3382/ps/pez480en
dc.identifier.pmid31424518en
local.contributor.firstnameKen
local.contributor.firstnameS Ken
local.contributor.firstnameCen
local.contributor.firstnameNen
local.contributor.firstnameR Aen
local.contributor.firstnameMen
local.contributor.firstnameS-Ben
local.subject.for2008070204 Animal Nutritionen
local.subject.for2008070203 Animal Managementen
local.subject.seo2008839901 Animal Welfareen
local.subject.seo2008920109 Infectious Diseasesen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolAdministrationen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailkgharib2@une.edu.auen
local.profile.emailsqassim2@une.edu.auen
local.profile.emailckeerqi2@une.edu.auen
local.profile.emailnmorga20@une.edu.auen
local.profile.emailrswick@une.edu.auen
local.profile.emailmchoct@une.edu.auen
local.profile.emailswu3@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeUnited States of Americaen
local.format.startpage6422en
local.format.endpage6432en
local.identifier.scopusid85076066720en
local.peerreviewedYesen
local.identifier.volume98en
local.identifier.issue12en
local.contributor.lastnameGharib-Naserien
local.contributor.lastnameKheraviien
local.contributor.lastnameKeerqinen
local.contributor.lastnameMorganen
local.contributor.lastnameSwicken
local.contributor.lastnameChocten
local.contributor.lastnameWuen
dc.identifier.staffune-id:kgharib2en
dc.identifier.staffune-id:sqassim2en
dc.identifier.staffune-id:ckeerqi2en
dc.identifier.staffune-id:nmorga20en
dc.identifier.staffune-id:rswicken
dc.identifier.staffune-id:mchocten
dc.identifier.staffune-id:swu3en
local.profile.orcid0000-0003-1740-7889en
local.profile.orcid0000-0002-4157-1489en
local.profile.orcid0000-0002-9663-2365en
local.profile.orcid0000-0003-3376-1677en
local.profile.orcid0000-0002-1790-6015en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:1959.11/27743en
local.date.onlineversion2019-08-19en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleTwo different Clostridium perfringens strains produce different levels of necrotic enteritis in broiler chickensen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorGharib-Naseri, Ken
local.search.authorKheravii, S Ken
local.search.authorKeerqin, Cen
local.search.authorMorgan, Nen
local.search.authorSwick, R Aen
local.search.authorChoct, Men
local.search.authorWu, S-Ben
local.istranslatedNoen
local.uneassociationYesen
local.atsiresearchNoen
local.sensitive.culturalNoen
local.identifier.wosid000504411800025en
local.year.available2019en
local.year.published2019en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/9637375e-cd4b-4bb2-b9ba-0ca3b5e1751fen
local.subject.for2020300303 Animal nutritionen
local.subject.for2020300302 Animal managementen
local.subject.seo2020109902 Animal welfareen
Appears in Collections:Journal Article
School of Environmental and Rural Science
Files in This Item:
2 files
File Description SizeFormat 
Show simple item record

SCOPUSTM   
Citations

39
checked on Aug 31, 2024

Page view(s)

2,594
checked on Aug 11, 2024

Download(s)

2
checked on Aug 11, 2024
Google Media

Google ScholarTM

Check

Altmetric


Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.