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Title: Limitations in the inverse association between Psychological Resilience and depression in prostate cancer patients experiencing chronic physiological stress
Contributor(s): Sharpley, Christopher  (author)orcid ; Christie, D R H (author); Bitsika, Vicki  (author); Agnew, Linda  (author)orcid ; Andronicos, Nicholas  (author)orcid ; McMillan, Mary  (author)orcid ; Richards, Timothy M (author)
Publication Date: 2018
Open Access: Yes
DOI: 10.1002/pon.4496Open Access Link
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Abstract: Objective: To investigate the effect of chronic stress as measured in cortisol concentrations upon the association between psychological resilience (PR) and depression in prostate cancer (PCa) patients. Methods: A total of 104 men with PCa completed inventories on PR, depression, and background factors, plus gave a sample of their saliva for cortisol assay. Results: The inverse correlation between PR and depression was present only for PCa patients with low or moderate concentrations of salivary cortisol (when classified as more than 1.0 SD below the mean vs within 1.0 SD of the group mean) but not for those men whose cortisol was >1.0 SD from the group mean. Specific PR factors and behaviours that made the greatest contribution to depression were identified for the low and moderate cortisol groups. Conclusions: These results suggest that there are particular aspects of PR that are most strongly related to depression, but that PR's inverse association with depression may be absent in participants with extreme chronic physiological stress.
Publication Type: Journal Article
Source of Publication: Psycho-Oncology, 27(1), p. 223-228
Publisher: John Wiley & Sons Ltd
Place of Publication: United Kingdom
ISSN: 1099-1611
Field of Research (FOR): 110903 Central Nervous System
Socio-Economic Outcome Codes: 920111 Nervous System and Disorders
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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Appears in Collections:Journal Article
School of Science and Technology

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