Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/20678
Title: | Synthesis and immunological evaluation of self-adjuvanting MUC1-macrophage activating lipopeptide 2 conjugate vaccine candidates | Contributor(s): | McDonald, David M (author); Wilkinson, Brendan (author)![]() |
Publication Date: | 2014 | DOI: | 10.1039/c4cc03510k | Handle Link: | https://hdl.handle.net/1959.11/20678 | Abstract: | We describe herein the synthesis and immunological evaluation of self-adjuvanting mucin 1 (MUC1)-macrophage activating lipopeptide 2 (MALP2) (glyco)peptide vaccine candidates. Vaccine constructs were shown to induce high titres of class-switched IgG antibodies in C57BL/6 mice after four immunisations despite the lack of a helper T cell epitope. | Publication Type: | Journal Article | Source of Publication: | Chemical Communications, 50(71), p. 10273-10276 | Publisher: | Royal Society of Chemistry | Place of Publication: | United Kingdom | ISSN: | 1364-548X 1359-7345 |
Fields of Research (FoR) 2008: | 030503 Organic Chemical Synthesis 030406 Proteins and Peptides 030401 Biologically Active Molecules |
Fields of Research (FoR) 2020: | 340407 Proteins and peptides 340503 Organic chemical synthesis 340401 Biologically active molecules |
Socio-Economic Objective (SEO) 2008: | 929999 Health not elsewhere classified 970103 Expanding Knowledge in the Chemical Sciences 970106 Expanding Knowledge in the Biological Sciences |
Socio-Economic Objective (SEO) 2020: | 280105 Expanding knowledge in the chemical sciences 280102 Expanding knowledge in the biological sciences |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
---|---|
Appears in Collections: | Journal Article |
Files in This Item:
File | Description | Size | Format |
---|
SCOPUSTM
Citations
41
checked on Jul 6, 2024
Page view(s)
1,290
checked on Jul 7, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.