Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/20675
Title: Synthesis of the Bacteriocin Glycopeptide Sublancin 168 and S-Glycosylated Variants
Contributor(s): Hsieh, Yves S Y (author); Wilkinson, Brendan  (author)orcid ; O'Connell, Mitchell R (author); Mackay, Joel P (author); Matthews, Jacqueline M (author); Payne, Richard J (author)
Publication Date: 2012
DOI: 10.1021/ol300557g
Handle Link: https://hdl.handle.net/1959.11/20675
Abstract: The synthesis of sublancin 168, a unique S-glucosylated bacteriocin antibiotic, is described. The natural product and two S-glycosylated variants were successfully prepared via native chemical ligation followed by folding. The synthetic glycopeptides were shown to possess primarily an α-helical secondary structure by CD and NMR studies.
Publication Type: Journal Article
Source of Publication: Organic Letters, 14(7), p. 1910-1913
Publisher: American Chemical Society
Place of Publication: United States of America
ISSN: 1523-7060
1523-7052
Field of Research (FOR): 030503 Organic Chemical Synthesis
030401 Biologically Active Molecules
030406 Proteins and Peptides
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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