Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/20595Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hsieh, Yves S Y | en |
| dc.contributor.author | Taleski, Deni | en |
| dc.contributor.author | Wilkinson, Brendan | en |
| dc.contributor.author | Wijeyewickrema, Lakshmi C | en |
| dc.contributor.author | Adams, Ty E | en |
| dc.contributor.author | Pike, Robert N | en |
| dc.contributor.author | Payne, Richard J | en |
| dc.date.accessioned | 2017-04-28T12:22:00Z | - |
| dc.date.issued | 2012 | - |
| dc.identifier.citation | Chemical Communications, 48(10), p. 1547-1549 | en |
| dc.identifier.issn | 1364-548X | en |
| dc.identifier.issn | 1359-7345 | en |
| dc.identifier.uri | https://hdl.handle.net/1959.11/20595 | - |
| dc.description.abstract | Synthesis of sulfated and unsulfated (glyco)peptide fragments of Hirudin P6 (a potent anticoagulant from the leech 'Hirudinaria manillensis') is described. The effect of O-glycosylation and tyrosine sulfation on thrombin binding and peptidolytic activity was investigated, together with the inhibition of fibrinogen cleavage. | en |
| dc.language | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.relation.ispartof | Chemical Communications | en |
| dc.title | Effect of O-glycosylation and tyrosinesulfation of leech-derived peptides on binding and inhibitory activity against thrombin | en |
| dc.type | Journal Article | en |
| dc.identifier.doi | 10.1039/c1cc14773k | en |
| dc.subject.keywords | Organic Chemical Synthesis | en |
| dc.subject.keywords | Proteins and Peptides | en |
| dc.subject.keywords | Biologically Active Molecules | en |
| local.contributor.firstname | Yves S Y | en |
| local.contributor.firstname | Deni | en |
| local.contributor.firstname | Brendan | en |
| local.contributor.firstname | Lakshmi C | en |
| local.contributor.firstname | Ty E | en |
| local.contributor.firstname | Robert N | en |
| local.contributor.firstname | Richard J | en |
| local.subject.for2008 | 030406 Proteins and Peptides | en |
| local.subject.for2008 | 030503 Organic Chemical Synthesis | en |
| local.subject.for2008 | 030401 Biologically Active Molecules | en |
| local.subject.seo2008 | 929999 Health not elsewhere classified | en |
| local.subject.seo2008 | 970103 Expanding Knowledge in the Chemical Sciences | en |
| local.subject.seo2008 | 970106 Expanding Knowledge in the Biological Sciences | en |
| local.profile.school | School of Science and Technology | en |
| local.profile.email | bwilkin7@une.edu.au | en |
| local.output.category | C1 | en |
| local.record.place | au | en |
| local.record.institution | University of New England | en |
| local.identifier.epublicationsrecord | une-20170323-115625 | en |
| local.publisher.place | United Kingdom | en |
| local.format.startpage | 1547 | en |
| local.format.endpage | 1549 | en |
| local.identifier.scopusid | 84855710913 | en |
| local.peerreviewed | Yes | en |
| local.identifier.volume | 48 | en |
| local.identifier.issue | 10 | en |
| local.contributor.lastname | Hsieh | en |
| local.contributor.lastname | Taleski | en |
| local.contributor.lastname | Wilkinson | en |
| local.contributor.lastname | Wijeyewickrema | en |
| local.contributor.lastname | Adams | en |
| local.contributor.lastname | Pike | en |
| local.contributor.lastname | Payne | en |
| dc.identifier.staff | une-id:bwilkin7 | en |
| local.profile.orcid | 0000-0003-1866-6540 | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.profile.role | author | en |
| local.identifier.unepublicationid | une:20789 | en |
| dc.identifier.academiclevel | Academic | en |
| local.title.maintitle | Effect of O-glycosylation and tyrosinesulfation of leech-derived peptides on binding and inhibitory activity against thrombin | en |
| local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
| local.search.author | Hsieh, Yves S Y | en |
| local.search.author | Taleski, Deni | en |
| local.search.author | Wilkinson, Brendan | en |
| local.search.author | Wijeyewickrema, Lakshmi C | en |
| local.search.author | Adams, Ty E | en |
| local.search.author | Pike, Robert N | en |
| local.search.author | Payne, Richard J | en |
| local.uneassociation | Unknown | en |
| local.year.published | 2012 | en |
| local.subject.for2020 | 340503 Organic chemical synthesis | en |
| local.subject.for2020 | 340407 Proteins and peptides | en |
| local.subject.for2020 | 340401 Biologically active molecules | en |
| local.subject.seo2020 | 280105 Expanding knowledge in the chemical sciences | en |
| local.subject.seo2020 | 280102 Expanding knowledge in the biological sciences | en |
| local.codeupdate.date | 2022-02-13T16:48:37.165 | en |
| local.codeupdate.eperson | bwilkin7@une.edu.au | en |
| local.codeupdate.finalised | true | en |
| local.original.for2020 | 340503 Organic chemical synthesis | en |
| local.original.for2020 | 340401 Biologically active molecules | en |
| local.original.for2020 | 340407 Proteins and peptides | en |
| local.original.seo2020 | 280105 Expanding knowledge in the chemical sciences | en |
| local.original.seo2020 | 280102 Expanding knowledge in the biological sciences | en |
| local.original.seo2020 | undefined | en |
| Appears in Collections: | Journal Article School of Science and Technology | |
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