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https://hdl.handle.net/1959.11/17616
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ruhnke, Isabelle | en |
dc.contributor.author | DeBiasio, John V | en |
dc.contributor.author | Suchodolski, Jan S | en |
dc.contributor.author | Newman, Shelley J | en |
dc.contributor.author | Musch, Mark W | en |
dc.contributor.author | Steiner, Joerg M | en |
dc.date.accessioned | 2015-07-06T16:44:00Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Research in Veterinary Science, 93(3), p. 1454-1461 | en |
dc.identifier.issn | 1532-2661 | en |
dc.identifier.issn | 0034-5288 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/17616 | - |
dc.description.abstract | Adapter-modified Ussing chambers have been used for assessment of endoscopically obtained intestinal biopsies in humans. The aim of this study was to evaluate the feasibility of an adapter-modified Ussing chamber for assessment of intestinal transport physiology in endoscopically-obtained colonic biopsies from cats and dogs. Fifteen colonic biopsies from four cats and 13 colonic biopsies from four dogs were transferred into a modified Ussing chamber and sequentially exposed to several compounds. Baseline mean ± SD conductance was measured. Changes of short circuit current (Δ/sc) were observed after exposure to glucose (number of feline biopsies that responded = 0/number of canine biopsies that responded = 4), phloridzin ('n' = 0/'n' = 7), histamine ('n' = 5/'n' = 12), serotonin (n = 7/n = 12), prostaglandin (n = 5/n = 7), forskolin (n = 7/n = 7), and ouabain (n = 9/n = 7). The adapter-modified Ussing chamber studied here enables investigation of transport physiology of endoscopically-obtained colonic biopsies from companion animals. However, we observed a large variability of results, suggesting that clinical use of this method is limited. | en |
dc.language | en | en |
dc.publisher | Elsevier Ltd | en |
dc.relation.ispartof | Research in Veterinary Science | en |
dc.title | Adapter-modified Ussing chamber enables evaluation of endoscopically-obtained colonic biopsy samples from cats and dogs | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1016/j.rvsc.2012.05.009 | en |
dc.subject.keywords | Veterinary Medicine | en |
dc.subject.keywords | Veterinary Diagnosis and Diagnostics | en |
local.contributor.firstname | Isabelle | en |
local.contributor.firstname | John V | en |
local.contributor.firstname | Jan S | en |
local.contributor.firstname | Shelley J | en |
local.contributor.firstname | Mark W | en |
local.contributor.firstname | Joerg M | en |
local.subject.for2008 | 070703 Veterinary Diagnosis and Diagnostics | en |
local.subject.for2008 | 070706 Veterinary Medicine | en |
local.subject.seo2008 | 860902 Veterinary Diagnostics | en |
local.profile.school | School of Environmental and Rural Science | en |
local.profile.email | iruhnke@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-20150702-031919 | en |
local.publisher.place | United Kingdom | en |
local.format.startpage | 1454 | en |
local.format.endpage | 1461 | en |
local.identifier.scopusid | 84866844943 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 93 | en |
local.identifier.issue | 3 | en |
local.contributor.lastname | Ruhnke | en |
local.contributor.lastname | DeBiasio | en |
local.contributor.lastname | Suchodolski | en |
local.contributor.lastname | Newman | en |
local.contributor.lastname | Musch | en |
local.contributor.lastname | Steiner | en |
dc.identifier.staff | une-id:iruhnke | en |
local.profile.orcid | 0000-0001-5423-9306 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:17832 | en |
local.identifier.handle | https://hdl.handle.net/1959.11/17616 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Adapter-modified Ussing chamber enables evaluation of endoscopically-obtained colonic biopsy samples from cats and dogs | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Ruhnke, Isabelle | en |
local.search.author | DeBiasio, John V | en |
local.search.author | Suchodolski, Jan S | en |
local.search.author | Newman, Shelley J | en |
local.search.author | Musch, Mark W | en |
local.search.author | Steiner, Joerg M | en |
local.uneassociation | Unknown | en |
local.year.published | 2012 | en |
local.subject.for2020 | 300904 Veterinary diagnosis and diagnostics | en |
local.subject.for2020 | 300907 Veterinary medicine (excl. urology) | en |
local.subject.seo2020 | 241602 Veterinary diagnostics | en |
Appears in Collections: | Journal Article School of Environmental and Rural Science |
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