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https://hdl.handle.net/1959.11/17565
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DC Field | Value | Language |
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dc.contributor.author | Pearson, Melissa | en |
dc.contributor.author | Dieberg, Gudrun | en |
dc.contributor.author | Smart, Neil | en |
dc.date.accessioned | 2015-06-25T17:09:00Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Archives of Physical Medicine and Rehabilitation, 96(7), p. 1339-1348 | en |
dc.identifier.issn | 1532-821X | en |
dc.identifier.issn | 0003-9993 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/17565 | - |
dc.description.abstract | Objective: To quantify improvements in walking performance commonly observed in patients with multiple sclerosis (pwMS), a systematic literature search and meta-analysis were conducted quantifying the expected benefits of exercise on walking ability in pwMS. Data Sources: Potential studies were identified by systematic search using PubMed (1966 to March 31, 2014), EMBASE (1974 to March 31, 2014), CINAHL (1998 to March 31, 2014), SPORTDiscus (1991 to March 31, 2014), and the Cochrane Central Register of Controlled Trials (1966 to March 31, 2014). The search used key concepts of "multiple sclerosis" AND "exercise." Study Selection: Randomized controlled trials of exercise training in adult pwMS. Data Extraction: Data on patient and study characteristics, walking ability, 10-m walk test (10mWT), timed 25-foot walk test (T25FW), 2-minute walk test (2MWT), 6-minute walk test (6MWT), and timed Up and Go (TUG) were extracted and archived. Data Synthesis: Data from 13 studies were included. In pwMS who exercised, significant improvements were found in walking speed, measured by the 10mWT (mean difference [MD] reduction in walking time of -1.76s; 95% confidence interval [CI], -2.47 to -1.06; P<.001), but no change in the T25FW (MD=-.59s; 95% CI, -2.55 to 1.36; P=.55). In pwMS who exercised, significant improvements were found in walking endurance as measured by the 6MWT and 2MWT, with an increased walking distance of MD=36.46m (95% CI, 15.14-57.79; P<.001) and MD=12.51m (95% CI, 4.79-20.23; P=.001), respectively. No improvement was found for TUG (MD=-1.05s; 95% CI, -2.19 to .09; P=.07). Conclusions: Our meta-analysis suggests that exercise improves walking speed and endurance in pwMS. | en |
dc.language | en | en |
dc.publisher | Elsevier Inc | en |
dc.relation.ispartof | Archives of Physical Medicine and Rehabilitation | en |
dc.title | Exercise as a Therapy for Improvement of Walking Ability in Adults With Multiple Sclerosis: A Meta-Analysis | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1016/j.apmr.2015.02.011 | en |
dc.subject.keywords | Exercise Physiology | en |
dc.subject.keywords | Neurology and Neuromuscular Diseases | en |
local.contributor.firstname | Melissa | en |
local.contributor.firstname | Gudrun | en |
local.contributor.firstname | Neil | en |
local.subject.for2008 | 110904 Neurology and Neuromuscular Diseases | en |
local.subject.for2008 | 110602 Exercise Physiology | en |
local.subject.seo2008 | 920111 Nervous System and Disorders | en |
local.profile.school | School of Science and Technology | en |
local.profile.school | School of Science and Technology | en |
local.profile.school | School of Science and Technology | en |
local.profile.email | mpears28@une.edu.au | en |
local.profile.email | gdieberg@une.edu.au | en |
local.profile.email | nsmart2@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-20150213-130322 | en |
local.publisher.place | United Kingdom | en |
local.format.startpage | 1339 | en |
local.format.endpage | 1348 | en |
local.identifier.scopusid | 84937515824 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 96 | en |
local.identifier.issue | 7 | en |
local.title.subtitle | A Meta-Analysis | en |
local.contributor.lastname | Pearson | en |
local.contributor.lastname | Dieberg | en |
local.contributor.lastname | Smart | en |
dc.identifier.staff | une-id:mpears28 | en |
dc.identifier.staff | une-id:gdieberg | en |
dc.identifier.staff | une-id:nsmart2 | en |
local.profile.orcid | 0000-0001-7191-182X | en |
local.profile.orcid | 0000-0002-8290-6409 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:17779 | en |
local.identifier.handle | https://hdl.handle.net/1959.11/17565 | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Exercise as a Therapy for Improvement of Walking Ability in Adults With Multiple Sclerosis | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Pearson, Melissa | en |
local.search.author | Dieberg, Gudrun | en |
local.search.author | Smart, Neil | en |
local.uneassociation | Unknown | en |
local.identifier.wosid | 000357762400021 | en |
local.year.published | 2015 | en |
local.subject.for2020 | 320905 Neurology and neuromuscular diseases | en |
local.subject.for2020 | 420702 Exercise physiology | en |
local.subject.seo2020 | 200101 Diagnosis of human diseases and conditions | en |
Appears in Collections: | Journal Article School of Science and Technology |
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