Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/14396
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dc.contributor.authorBolormaa, Sen
dc.contributor.authorPryce, J Een
dc.contributor.authorHarrison, B Een
dc.contributor.authorReverter, Aen
dc.contributor.authorHerd, Robert Men
dc.contributor.authorTier, Bruceen
dc.contributor.authorGraser, Hans-Ulrichen
dc.contributor.authorGoddard, M Een
dc.contributor.authorKemper, Ken
dc.contributor.authorSavin, Sen
dc.contributor.authorHayes, B Jen
dc.contributor.authorBarendse, Wen
dc.contributor.authorZhang, Yuandanen
dc.contributor.authorReich, C Men
dc.contributor.authorMason, B Aen
dc.contributor.authorBunch, R Jen
dc.date.accessioned2014-03-28T10:41:00Z
dc.date.issued2013en
dc.identifier.citationJournal of Animal Science, 91(7), p. 3088-3104en
dc.identifier.issn0021-8812en
dc.identifier.issn1525-3163en
dc.identifier.urihttps://hdl.handle.net/1959.11/14396en
dc.description.abstractThe aim of this study was to assess the accuracy of genomic predictions for 19 traits including feed efficiency, growth, and carcass and meat quality traits in beef cattle. The 10,181 cattle in our study had real or imputed genotypes for 729,068 SNP although not all cattle were measured for all traits. Animals included 'Bos taurus', Brahman, composite, and crossbred animals. Genomic EBV (GEBV) were calculated using 2 methods of genomic prediction [BayesR and genomic BLUP (GBLUP)] either using a common training dataset for all breeds or using a training dataset comprising only animals of the same breed. Accuracies of GEBV were assessed using 5-fold cross-validation. The accuracy of genomic prediction varied by trait and by method. Traits with a large number of recorded and genotyped animals and with high heritability gave the greatest accuracy of GEBV. Using GBLUP, the average accuracy was 0.27 across traits and breeds, but the accuracies between breeds and between traits varied widely. When the training population was restricted to animals from the same breed as the validation population, GBLUP accuracies declined by an average of 0.04. The greatest decline in accuracy was found for the 4 composite breeds. The BayesR accuracies were greater by an average of 0.03 than GBLUP accuracies, particularly for traits with known genes of moderate to large effect mutations segregating. The accuracies of 0.43 to 0.48 for IGF-I traits were among the greatest in the study. Although accuracies are low compared with those observed in dairy cattle, genomic selection would still be beneficial for traits that are hard to improve by conventional selection, such as tenderness and residual feed intake. BayesR identified many of the same quantitative trait loci as a genomewide association study but appeared to map them more precisely. All traits appear to be highly polygenic with thousands of SNP independently associated with each trait.en
dc.languageenen
dc.publisherAmerican Society of Animal Scienceen
dc.relation.ispartofJournal of Animal Scienceen
dc.titleAccuracy of prediction of genomic breeding values for residual feed intake and carcass and meat quality traits in 'Bos taurus', 'Bos indicus', and composite beef cattleen
dc.typeJournal Articleen
dc.identifier.doi10.2527/jas.2012-5827en
dcterms.accessRightsGolden
dc.subject.keywordsAnimal Breedingen
dc.subject.keywordsGenomicsen
local.contributor.firstnameSen
local.contributor.firstnameJ Een
local.contributor.firstnameB Een
local.contributor.firstnameAen
local.contributor.firstnameRobert Men
local.contributor.firstnameBruceen
local.contributor.firstnameHans-Ulrichen
local.contributor.firstnameM Een
local.contributor.firstnameKen
local.contributor.firstnameSen
local.contributor.firstnameB Jen
local.contributor.firstnameWen
local.contributor.firstnameYuandanen
local.contributor.firstnameC Men
local.contributor.firstnameB Aen
local.contributor.firstnameR Jen
local.subject.for2008060408 Genomicsen
local.subject.for2008070201 Animal Breedingen
local.subject.seo2008830301 Beef Cattleen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.emailrherd3@une.edu.auen
local.profile.emailbtier@une.edu.auen
local.profile.emailhgraser@une.edu.auen
local.profile.emailyzhang4@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20140311-141553en
local.publisher.placeUnited States of Americaen
local.format.startpage3088en
local.format.endpage3104en
local.peerreviewedYesen
local.identifier.volume91en
local.identifier.issue7en
local.access.fulltextYesen
local.contributor.lastnameBolormaaen
local.contributor.lastnamePryceen
local.contributor.lastnameHarrisonen
local.contributor.lastnameReverteren
local.contributor.lastnameHerden
local.contributor.lastnameTieren
local.contributor.lastnameGraseren
local.contributor.lastnameGoddarden
local.contributor.lastnameKemperen
local.contributor.lastnameSavinen
local.contributor.lastnameHayesen
local.contributor.lastnameBarendseen
local.contributor.lastnameZhangen
local.contributor.lastnameReichen
local.contributor.lastnameMasonen
local.contributor.lastnameBunchen
dc.identifier.staffune-id:rherd3en
dc.identifier.staffune-id:btieren
dc.identifier.staffune-id:hgraseren
dc.identifier.staffune-id:yzhang4en
local.profile.orcid0000-0003-4689-5519en
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local.identifier.unepublicationidune:14611en
local.identifier.handlehttps://hdl.handle.net/1959.11/14396en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleAccuracy of prediction of genomic breeding values for residual feed intake and carcass and meat quality traits in 'Bos taurus', 'Bos indicus', and composite beef cattleen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/23658330en
local.description.statisticsepubsVisitors: 674<br />Views: 1080<br />Downloads: 1en
local.search.authorBolormaa, Sen
local.search.authorPryce, J Een
local.search.authorHarrison, B Een
local.search.authorReverter, Aen
local.search.authorHerd, Robert Men
local.search.authorTier, Bruceen
local.search.authorGraser, Hans-Ulrichen
local.search.authorGoddard, M Een
local.search.authorKemper, Ken
local.search.authorSavin, Sen
local.search.authorHayes, B Jen
local.search.authorBarendse, Wen
local.search.authorZhang, Yuandanen
local.search.authorReich, C Men
local.search.authorMason, B Aen
local.search.authorBunch, R Jen
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