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|Title:||Efficacy of inspiratory muscle training in chronic heart failure patients: A systematic review and meta-analysis||Contributor(s):||Smart, Neil (author) ; Giallauria, Francesco (author); Dieberg, Gudrun (author)||Publication Date:||2013||DOI:||10.1016/j.ijcard.2012.04.029||Handle Link:||https://hdl.handle.net/1959.11/13301||Abstract:||Introduction: Inspiratory muscle training (IMT) offers an alternative to exercise training (ExT) in the most severely deconditioned heart failure patients who are unable to exercise. We conducted a meta-analysis to determine magnitude of change in peak VO₂, six minute walk distance (6MWD), Quality of Life measured by the Minnesota Living with Heart Failure Questionnaire (MLWHFQ), maximal inspiratory pressure (PI max) and ventilatory equivalent for carbon dioxide (VE/VCO₂ slope) with IMT. Methods: A systematic search was conducted of randomized, controlled trials of IMT therapy in CHF patients using Medline (Ovid) (1950-February 2012), Embase.com (1974-February 2012), Cochrane Central Register of Controlled Trials and CINAHL (1981-February 2012). The search strategy included a mix of MeSH and free text terms for the key concepts heart failure, inspiratory or respiratory muscle training, exercise training. Results: The eleven included studies contained data on 287 participants: 148 IMT participants and 139 sham or sedentary control. Compared to control groups, CHF patients undergoing IMT showed a significant improvement in peak VO₂ (+ 1.83 ml kg⁻¹ min⁻¹, 95% C.I. 1.33 to 2.32 ml kg⁻¹ min⁻¹, p < 0.00001); 6MWD (+ 34.35 m, 95% C.I. 22.45 to 46.24 m, p < 0.00001); MLWHFQ (- 12.25, 95% C.I. - 17.08 to - 7.43, p < 0.00001); PImax (+ 20.01, 95% C.I. 13.96 to 26.06, p < 0.00001); and VE/VCO₂ slope (- 2.28, 95% C.I. - 3.25 to - 1.30, p < 0.00001). Conclusions: IMT improves cardio-respiratory fitness and quality of life to a similar magnitude to conventional exercise training and may provide an initial alternative to the more severely de-conditioned CHF patients who may then transition to conventional ExT.||Publication Type:||Journal Article||Source of Publication:||International Journal of Cardiology, 167(4), p. 1502-1507||Publisher:||Elsevier Ireland Ltd||Place of Publication:||Ireland||ISSN:||0167-5273
|Field of Research (FOR):||110201 Cardiology (incl Cardiovascular Diseases)||Socio-Economic Outcome Codes:||920103 Cardiovascular System and Diseases||Peer Reviewed:||Yes||HERDC Category Description:||C1 Refereed Article in a Scholarly Journal||Statistics to Oct 2018:||Visitors: 95
|Appears in Collections:||Journal Article|
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