Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/12302
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dc.contributor.authorGuy, Saritaen
dc.contributor.authorThomson, Peter Cen
dc.contributor.authorHermesch, Susanneen
dc.date.accessioned2013-03-18T09:40:00Z-
dc.date.issued2012en
dc.identifier.citationFrontiers in Genetics, v.3, p. 1-9en
dc.identifier.issn1664-8021en
dc.identifier.urihttps://hdl.handle.net/1959.11/12302-
dc.description.abstractThe benefits of improved health and welfare in pigs have driven refinements in management and selection practices, one of which is the production of pig phenotypes that can maintain health and productivity by improving response against pathogens. Selection has traditionally been made for host resistance; but the alternative host defence mechanism - host tolerance - is now being considered, as breeding for disease tolerance allows maintenance of high performance across environments of increasing pathogenic load. A distinction must be made between these two mechanisms as they vary in their influence on host-pathogen interactions and pathogen evolution, and consequently on the results of breeding programs. Many pig production studies have failed to distinguish between resistance and tolerance; although a distinction may not always be possible. This article reviews current perspectives in selective breeding for disease resistance and tolerance in growing pigs, and the attendant industry implications. To assess the viability of breeding for resistance and/or tolerance for improved response to disease and other environmental challenges, we propose the use of routine farm records, instead of data measurements taken from laboratory experiments. Consequently, a number of factors need to be taken into account simultaneously for a multidimensional modeling approach. This includes not only genotype and disease variables, but also descriptors of the environment, as well as any possible interactions. It may not be feasible to record individual pathogen loads, and therefore true tolerance, on farm using routinely collected data. However, it may be estimated with group (farm) means, or other proxy measures. Although this results in a bias, this may still be useful for modeling and quantifying resistance and tolerance. We can then quantify success of selection, and this may enable us to decide whether to select for disease resistance versus disease tolerance.en
dc.languageenen
dc.publisherFrontiers Research Foundationen
dc.relation.ispartofFrontiers in Geneticsen
dc.titleSelection of pigs for improved coping with health and environmental challenges: breeding for resistance or tolerance?en
dc.typeJournal Articleen
dc.identifier.doi10.3389/fgene.2012.00281en
dcterms.accessRightsGolden
dc.subject.keywordsAnimal Breedingen
local.contributor.firstnameSaritaen
local.contributor.firstnamePeter Cen
local.contributor.firstnameSusanneen
local.subject.for2008070201 Animal Breedingen
local.subject.seo2008830308 Pigsen
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.emailsarita.guy@une.edu.auen
local.profile.emailSusanne.Hermesch@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20130308-15566en
local.publisher.placeSwitzerlanden
local.identifier.runningnumberArticle 281en
local.format.startpage1en
local.format.endpage9en
local.peerreviewedYesen
local.identifier.volume3en
local.title.subtitlebreeding for resistance or tolerance?en
local.access.fulltextYesen
local.contributor.lastnameGuyen
local.contributor.lastnameThomsonen
local.contributor.lastnameHermeschen
dc.identifier.staffune-id:sguy4en
dc.identifier.staffune-id:skahtenben
local.profile.orcid0000-0002-5553-1808en
local.profile.orcid0000-0002-9647-5988en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:12508en
dc.identifier.academiclevelAcademicen
local.title.maintitleSelection of pigs for improved coping with health and environmental challengesen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.description.statisticsepubsVisitors: 116<br />Views: 118<br />Downloads: 1en
local.search.authorGuy, Saritaen
local.search.authorThomson, Peter Cen
local.search.authorHermesch, Susanneen
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Journal Article
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