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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/12031
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dc.contributor.authorGiarrusso, Marilena Aen
dc.contributor.authorTaylor, Michelle Ken
dc.contributor.authorZiogas, Jamesen
dc.contributor.authorBrody, Kate Men
dc.contributor.authorMacdougall, Phoebe Een
dc.contributor.authorSchiesser, Carl Hen
dc.date.accessioned2013-02-11T14:13:00Z-
dc.date.issued2012-
dc.identifier.citationAsian Journal of Organic Chemistry, 1(3), p. 274-279en
dc.identifier.issn2193-5815en
dc.identifier.issn2193-5807en
dc.identifier.urihttps://hdl.handle.net/1959.11/12031-
dc.description.abstractFluorescent selective angiotensin AT₁ receptor antagonists (sartans) that contain naphthalene (6, 7, 10, and 11), anthracene (12 and 14), acenaphthene (13 and 15), and coumarin (8 and 9) substituents have been prepared and their preliminary pharmacology evaluated in Chinese hamster ovary (CHO) cell based assays. Compounds 6-15 proved to be effective sartans with pKB estimates in the range of 6.7-10.5; their potential as cellular imaging agents is also discussed.en
dc.languageenen
dc.publisherWiley-VCH Verlag GmbH & Co KGaAen
dc.relation.ispartofAsian Journal of Organic Chemistryen
dc.titleFluorescent Angiotensin AT₁ Receptor Antagonistsen
dc.typeJournal Articleen
dc.identifier.doi10.1002/ajoc.201200064en
dc.subject.keywordsOrganic Chemical Synthesisen
dc.subject.keywordsBiologically Active Moleculesen
local.contributor.firstnameMarilena Aen
local.contributor.firstnameMichelle Ken
local.contributor.firstnameJamesen
local.contributor.firstnameKate Men
local.contributor.firstnamePhoebe Een
local.contributor.firstnameCarl Hen
local.subject.for2008030401 Biologically Active Moleculesen
local.subject.for2008030503 Organic Chemical Synthesisen
local.subject.seo2008970103 Expanding Knowledge in the Chemical Sciencesen
local.profile.schoolChemistryen
local.profile.schoolSchool of Science and Technologyen
local.profile.emailmtaylo53@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20121207-150126en
local.publisher.placeGermanyen
local.format.startpage274en
local.format.endpage279en
local.identifier.scopusid84895128482en
local.peerreviewedYesen
local.identifier.volume1en
local.identifier.issue3en
local.contributor.lastnameGiarrussoen
local.contributor.lastnameTayloren
local.contributor.lastnameZiogasen
local.contributor.lastnameBrodyen
local.contributor.lastnameMacdougallen
local.contributor.lastnameSchiesseren
dc.identifier.staffune-id:mtaylo53en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:12234en
dc.identifier.academiclevelAcademicen
local.title.maintitleFluorescent Angiotensin AT₁ Receptor Antagonistsen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorGiarrusso, Marilena Aen
local.search.authorTaylor, Michelle Ken
local.search.authorZiogas, Jamesen
local.search.authorBrody, Kate Men
local.search.authorMacdougall, Phoebe Een
local.search.authorSchiesser, Carl Hen
local.uneassociationUnknownen
local.year.published2012en
local.subject.for2020340401 Biologically active moleculesen
local.subject.for2020340503 Organic chemical synthesisen
local.subject.seo2020280105 Expanding knowledge in the chemical sciencesen
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