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https://hdl.handle.net/1959.11/10998
Title: | Stress Proteins in Human Breast Cancer | Contributor(s): | Shipp, Christopher (author); Watson, Kenneth (author); Jones, Graham L (author) | Publication Date: | 2008 | Handle Link: | https://hdl.handle.net/1959.11/10998 | Abstract: | In this study we investigated stress protein (hsp70 and 90) expression in tumour tissue taken from various breast cancer patients and compared this with expression in a cultured breast cancer cell line as well as in normal peripheral lymphocytes with and without heat shock treatment. Given the importance of hsp90 in the steroid receptor complex we compared the effect of the anticancer drug geldanamycin on the assembly of the hsp90 complex in breast tumour tissue, breast cancer cells and normal lymphocytes in short term culture before and after heat shock. | Publication Type: | Conference Publication | Conference Details: | EMBO 2008 Conference: European Molecular Biology Organization 2008 conference on Cellular Signaling and Molecular Medicine, Cavtat, Croatia, 29th May - 4th June, 2008 | Source of Publication: | EMBO Meeting on Cellular Signaling and Molecular Medicine Abstracts, p. 114-115 | Publisher: | Digital Studio Akvarij | Place of Publication: | Dubrovnik, Croatia | Fields of Research (FoR) 2008: | 110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) | Socio-Economic Objective (SEO) 2008: | 920102 Cancer and Related Disorders | HERDC Category Description: | E3 Extract of Scholarly Conference Publication |
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Appears in Collections: | Conference Publication |
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