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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/8494
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dc.contributor.authorMurison, Robert Daviden
dc.contributor.authorFalzon, Gregoryen
dc.contributor.authorPearson, Sarah Jayneen
dc.date.accessioned2011-09-13T17:02:00Z-
dc.date.issued2008-
dc.identifier.citationPhysics in Medicine and Biology, 53(23), p. 6641-6652en
dc.identifier.issn1361-6560en
dc.identifier.issn0031-9155en
dc.identifier.urihttps://hdl.handle.net/1959.11/8494-
dc.description.abstractSecond harmonic generation microscopy was performed on both normal and diseased breast tissue. Differences in the collagen fibre shape between normal, benign and malignant breast tissue were compared and quantified using elliptical Fourier analysis. Principal shape analysis of these coefficients provided an understanding of the key differences in collagen fibre shape between the three tissue types. A Gaussian model was also used to associate the shape of the fibre with the probability that it had been sampled from malignant breast tissue. These results provide quantitative evidence for the alteration of collagen fibre shape in both benign and malignant breast tissue.en
dc.languageenen
dc.publisherInstitute of Physics Publishing Ltden
dc.relation.ispartofPhysics in Medicine and Biologyen
dc.titleAnalysis of collagen fibre shape changes in breast canceren
dc.typeJournal Articleen
dc.identifier.doi10.1088/0031-9155/53/23/001en
dc.subject.keywordsBiological Mathematicsen
local.contributor.firstnameRobert Daviden
local.contributor.firstnameGregoryen
local.contributor.firstnameSarah Jayneen
local.subject.for2008010202 Biological Mathematicsen
local.subject.seo2008920102 Cancer and Related Disordersen
local.profile.schoolSchool of Science and Technologyen
local.profile.schoolSchool of Science and Technologyen
local.profile.schoolSchool of Science and Technologyen
local.profile.emailrmurison@une.edu.auen
local.profile.emailgfalzon2@une.edu.auen
local.profile.emailspearson@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordpes:7162en
local.publisher.placeUnited Kingdomen
local.format.startpage6641en
local.format.endpage6652en
local.identifier.scopusid58149263235en
local.peerreviewedYesen
local.identifier.volume53en
local.identifier.issue23en
local.contributor.lastnameMurisonen
local.contributor.lastnameFalzonen
local.contributor.lastnamePearsonen
dc.identifier.staffune-id:rmurisonen
dc.identifier.staffune-id:gfalzon2en
dc.identifier.staffune-id:spearsonen
local.profile.orcid0000-0002-1989-9357en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:8671en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleAnalysis of collagen fibre shape changes in breast canceren
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorMurison, Robert Daviden
local.search.authorFalzon, Gregoryen
local.search.authorPearson, Sarah Jayneen
local.uneassociationUnknownen
local.identifier.wosid000260859000001en
local.year.published2008en
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