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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/8327
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dc.contributor.authorHanstock, Tanyaen
dc.contributor.authorHirneth, SJen
dc.contributor.authorKable, CJen
dc.contributor.authorGarg, MLen
dc.contributor.authorHazell, PLen
dc.contributor.authorClayton, EHen
dc.date.accessioned2011-08-04T17:22:00Z-
dc.date.issued2008-
dc.identifier.citationAustralian & New Zealand Journal of Psychiatry, 42(Supplement 3), p. A45-A45en
dc.identifier.issn1440-1614en
dc.identifier.issn0004-8674en
dc.identifier.urihttps://hdl.handle.net/1959.11/8327-
dc.description.abstractBackground: Supplementation with long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), may be beneficial in the treatment of depression in children and bipolar disorder (BD) in adults. Aims: To examine the change in symptoms of mania and depression in participants with juvenile BD (JBD) following supplementation with LCn-3PUFA. Method: Eighteen participants with JBD received supplements containing 1.92 g day⁻¹ LCn-3PUFA, including 360 mg day⁻¹ EPA and 1560 mg day⁻¹ DHA, for 6 weeks. Fasting Red Blood Cell (RBC) LCn-3PUFA, mania, depression and global function were measured before and after supplementation. Results: RBC EPA and DHA increased significantly following supplementation. Symptoms of mania and depression were significantly lower and global functioning was significantly higher following supplementation. Changes in RBC LCn-3PUFA were not significantly related to changes in mania or depression. Conclusion: Supplementation with omega-3 was associated with a reduction in mania and depression in participants with JBD when given in an open-label manner. A larger randomised controlled trial appears warranted in this participant population.en
dc.languageenen
dc.publisherInforma Healthcareen
dc.relation.ispartofAustralian & New Zealand Journal of Psychiatryen
dc.titleOmega-3 supplementation in juvenile bipolar disorderen
dc.typeJournal Articleen
dc.subject.keywordsHealth, Clinical and Counselling Psychologyen
local.contributor.firstnameTanyaen
local.contributor.firstnameSJen
local.contributor.firstnameCJen
local.contributor.firstnameMLen
local.contributor.firstnamePLen
local.contributor.firstnameEHen
local.subject.for2008170106 Health, Clinical and Counselling Psychologyen
local.subject.seo2008920410 Mental Healthen
local.subject.seo2008920411 Nutritionen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.emailthansto2@une.edu.auen
local.output.categoryC4en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20110331-154527en
local.publisher.placeAustraliaen
local.format.startpageA45en
local.format.endpageA45en
local.identifier.volume42en
local.identifier.issueSupplement 3en
local.contributor.lastnameHanstocken
local.contributor.lastnameHirnethen
local.contributor.lastnameKableen
local.contributor.lastnameGargen
local.contributor.lastnameHazellen
local.contributor.lastnameClaytonen
dc.identifier.staffune-id:thansto2en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:8503en
dc.identifier.academiclevelAcademicen
local.title.maintitleOmega-3 supplementation in juvenile bipolar disorderen
local.output.categorydescriptionC4 Letter of Noteen
local.relation.doi10.1080/00048670802549638en
local.search.authorHanstock, Tanyaen
local.search.authorHirneth, SJen
local.search.authorKable, CJen
local.search.authorGarg, MLen
local.search.authorHazell, PLen
local.search.authorClayton, EHen
local.uneassociationUnknownen
local.year.published2008en
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