Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/8140
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Avery, Thomas D | en |
dc.contributor.author | Greatrex, Ben | en |
dc.contributor.author | Pederson, Daniel Sejer | en |
dc.contributor.author | Taylor, Dennis K | en |
dc.contributor.author | Tiekink, Edward R T | en |
dc.date.accessioned | 2011-07-22T14:32:00Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | The Journal of Organic Chemistry, 73(7), p. 2633-2640 | en |
dc.identifier.issn | 1520-6904 | en |
dc.identifier.issn | 0022-3263 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/8140 | - |
dc.description.abstract | 1,2-Dioxines react with glycine-derived phosphonate nucleophiles via a multistep cascade reaction to give β-cyclopropyl amino acid derivatives in good yield with excellent control of the cyclopropane stereocentres. The cyclopropyl ketones were oxidized to the corresponding carboxylic esters using Baeyer−Villiger conditions. Standard deprotection protocols produced a series of known β-cyclopropyl amino acids that are selective and potent agonists or antagonists of the metabotropic glutamate receptors in excellent yields. | en |
dc.language | en | en |
dc.publisher | American Chemical Society | en |
dc.relation.ispartof | The Journal of Organic Chemistry | en |
dc.title | A Concise Route to β-Cyclopropyl Amino Acids Utilizing 1,2-Dioxines and Stabilized Phosphonate Nucleophiles | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1021/jo7024256 | en |
dc.subject.keywords | Organic Chemical Synthesis | en |
local.contributor.firstname | Thomas D | en |
local.contributor.firstname | Ben | en |
local.contributor.firstname | Daniel Sejer | en |
local.contributor.firstname | Dennis K | en |
local.contributor.firstname | Edward R T | en |
local.subject.for2008 | 030503 Organic Chemical Synthesis | en |
local.subject.seo2008 | 970103 Expanding Knowledge in the Chemical Sciences | en |
local.profile.school | School of Rural Medicine | en |
local.profile.email | bgreatre@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-20110325-125232 | en |
local.publisher.place | United States of America | en |
local.format.startpage | 2633 | en |
local.format.endpage | 2640 | en |
local.identifier.scopusid | 41649099340 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 73 | en |
local.identifier.issue | 7 | en |
local.contributor.lastname | Avery | en |
local.contributor.lastname | Greatrex | en |
local.contributor.lastname | Pederson | en |
local.contributor.lastname | Taylor | en |
local.contributor.lastname | Tiekink | en |
dc.identifier.staff | une-id:bgreatre | en |
local.profile.orcid | 0000-0002-0356-4966 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:8315 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | A Concise Route to β-Cyclopropyl Amino Acids Utilizing 1,2-Dioxines and Stabilized Phosphonate Nucleophiles | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Avery, Thomas D | en |
local.search.author | Greatrex, Ben | en |
local.search.author | Pederson, Daniel Sejer | en |
local.search.author | Taylor, Dennis K | en |
local.search.author | Tiekink, Edward R T | en |
local.uneassociation | Unknown | en |
local.year.published | 2008 | en |
Appears in Collections: | Journal Article |
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