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Title: Changes in concentrations of follistatin in maternal plasma and foetal fluids during pregnancy and parturition in sheep
Contributor(s): Xia, Yin (author); O'Shea, T (author); McFarlane, James R (author)orcid 
Publication Date: 2009
DOI: 10.1016/j.anireprosci.2008.08.022
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Abstract: Studies have shown that follistatin may be involved in the regulation of ovarian development, pregnancy and parturition. The aim of the present study was to measure follistatin levels in maternal plasma and foetal fluids during pregnancy and parturition in sheep. Using a previously described follistatin radioimmunoassay, we found that follistatin in foetal plasma and allantoic fluid was higher in the female than in the male at days 50–75 of gestation. Follistatin concentrations in maternal plasma declined from −9 to −3 h before the completion of lamb delivery, and increased from 21 to 39 h after parturition. These results suggest that follistatin may play a role in femaleness development, and that follistatin may be involved in the mechanism of normal parturition and in regulation of the tissue repair after parturition.
Publication Type: Journal Article
Source of Publication: Animal Reproduction Science, v.114, p. 148-156
Publisher: Elsevier BV
Place of Publication: The Netherlands
ISSN: 0378-4320
Field of Research (FOR): 060603 Animal Physiology - Systems
Socio-Economic Outcome Codes: 970111 Expanding Knowledge in the Medical and Health Sciences
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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