Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/59120
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dc.contributor.authorPuschnig, Johannesen
dc.contributor.authorJevric, Martynen
dc.contributor.authorSumby, Christopher Jen
dc.contributor.authorGreatrex, Ben Wen
dc.date.accessioned2024-05-08T23:06:19Z-
dc.date.available2024-05-08T23:06:19Z-
dc.date.issued2024-01-19-
dc.identifier.citationThe Journal of Organic Chemistry, 89(2), p. 1315-1319en
dc.identifier.issn1520-6904en
dc.identifier.issn0022-3263en
dc.identifier.urihttps://hdl.handle.net/1959.11/59120-
dc.description.abstract<p>The intramolecular enamine-Mizoroki–Heck reaction allows for the construction of nitrogen-containing heterocycles, although the related intermolecular version is less known. The reactions of enamines derived from Cyrene were investigated under Mizoroki–Heck conditions. An optimization study was used to identify that 1.5 mol % Pd(dba)<sub>2</sub> with PCy<sub>3</sub> in xylene at reflux temperature gave the highest yield with electron-rich aryl iodides. Arylation occurred predominantly at the C–N center of the enamine, while the diastereoselectivity was dependent on the nitrogen substitution in the enamine.</p>en
dc.languageenen
dc.publisherAmerican Chemical Societyen
dc.relation.ispartofThe Journal of Organic Chemistryen
dc.titleIntermolecular Enamine Mizoroki–Heck Reactions on a Bio-Derived Scaffolden
dc.typeJournal Articleen
dc.identifier.doi10.1021/acs.joc.3c02415en
local.contributor.firstnameJohannesen
local.contributor.firstnameMartynen
local.contributor.firstnameChristopher Jen
local.contributor.firstnameBen Wen
local.relation.isfundedbyARCen
local.profile.schoolSchool of Rural Medicineen
local.profile.schoolSchool of Rural Medicineen
local.profile.emailmjevric@une.edu.auen
local.profile.emailbgreatre@une.edu.auen
local.output.categoryC1en
local.grant.numberE210100163en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeUnited States of Americaen
local.format.startpage1315en
local.format.endpage1319en
local.peerreviewedYesen
local.identifier.volume89en
local.identifier.issue2en
local.contributor.lastnamePuschnigen
local.contributor.lastnameJevricen
local.contributor.lastnameSumbyen
local.contributor.lastnameGreatrexen
dc.identifier.staffune-id:mjevricen
dc.identifier.staffune-id:bgreatreen
local.profile.orcid0000-0002-0356-4966en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:1959.11/59120en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleIntermolecular Enamine Mizoroki–Heck Reactions on a Bio-Derived Scaffolden
local.relation.fundingsourcenoteThe Australian Government with a Research Training Program (RTP) Scholarshipen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.relation.grantdescriptionARC/E210100163en
local.search.authorPuschnig, Johannesen
local.search.authorJevric, Martynen
local.search.authorSumby, Christopher Jen
local.search.authorGreatrex, Ben Wen
local.uneassociationYesen
local.atsiresearchNoen
local.sensitive.culturalNoen
local.year.published2024en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/daf05824-d75d-423c-9cf8-346bba61163ben
local.subject.for20203405 Organic chemistryen
local.subject.seo2020tbden
local.profile.affiliationtypeUNE Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeExternal Affiliationen
local.profile.affiliationtypeUNE Affiliationen
local.date.moved2024-05-09en
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