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https://hdl.handle.net/1959.11/3987
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Meiser, B | en |
dc.contributor.author | Collins, V | en |
dc.contributor.author | Warren, R | en |
dc.contributor.author | Gaff, C | en |
dc.contributor.author | James, D | en |
dc.contributor.author | St John, B | en |
dc.contributor.author | Young, M | en |
dc.contributor.author | Harrop, K | en |
dc.contributor.author | Brown, Judith Elizabeth | en |
dc.date.accessioned | 2009-12-22T16:46:00Z | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Clinical Genetics, 66(6), p. 502-511 | en |
dc.identifier.issn | 0009-9163 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/3987 | - |
dc.description.abstract | The psychological impact of predictive genetic testing for hereditary non-polyposis colorectal cancer was assessed in 114 individuals (32 carriers and 82 non-carriers) attending familial cancer clinics, using mailed self-administered questionnaires prior to, 2 weeks, 4 months and 12 months after carrier status disclosure. Compared to baseline, carriers showed a significant increase in mean scores for intrusive and avoidant thoughts about colorectal cancer 2 weeks (t=2.49; p=0.014) and a significant decrease in mean depression scores 2 weeks post-notification of result (t=-3.98; p<9.001) and 4 months post-notification of result (t=-3.22; p=0.002). For non-carriers, significant decreases in mean scores for intrusive and avoidant thoughts about colorectal cancer were observed at all follow-up assessment time points relative to baseline. Non-carriers also showed significant decreases from baseline in mean depression scores 2 weeks, 4 months and 12 months post-notification. Significant decreases from baseline for mean state anxiety scores were also observed for non-carriers 2 weeks post-notification (t=-3.99; p>0.001). These data indicate that predictive genetic testing for HNPCC leads to psychological benefits against non-carriers, and no adverse psychological outcomes were observed amongst carriers. | en |
dc.language | en | en |
dc.publisher | Blackwell Publishing Ltd | en |
dc.relation.ispartof | Clinical Genetics | en |
dc.title | Psychological impact of genetic testing for hereditary non-polyposis colorectal cancer | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1111/j.1399-0004.2004.00339.x | en |
dc.subject.keywords | Sociology | en |
local.contributor.firstname | B | en |
local.contributor.firstname | V | en |
local.contributor.firstname | R | en |
local.contributor.firstname | C | en |
local.contributor.firstname | D | en |
local.contributor.firstname | B | en |
local.contributor.firstname | M | en |
local.contributor.firstname | K | en |
local.contributor.firstname | Judith Elizabeth | en |
local.subject.for2008 | 160899 Sociology not elsewhere classified | en |
local.subject.seo2008 | 970116 Expanding Knowledge through Studies of Human Society | en |
local.profile.school | School of Behavioural, Cognitive and Social Sciences | en |
local.profile.email | jbrown42@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | pes:5327 | en |
local.publisher.place | Denmark | en |
local.format.startpage | 502 | en |
local.format.endpage | 511 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 66 | en |
local.identifier.issue | 6 | en |
local.contributor.lastname | Meiser | en |
local.contributor.lastname | Collins | en |
local.contributor.lastname | Warren | en |
local.contributor.lastname | Gaff | en |
local.contributor.lastname | James | en |
local.contributor.lastname | St John | en |
local.contributor.lastname | Young | en |
local.contributor.lastname | Harrop | en |
local.contributor.lastname | Brown | en |
dc.identifier.staff | une-id:jbrown42 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:4084 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Psychological impact of genetic testing for hereditary non-polyposis colorectal cancer | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Meiser, B | en |
local.search.author | Collins, V | en |
local.search.author | Warren, R | en |
local.search.author | Gaff, C | en |
local.search.author | James, D | en |
local.search.author | St John, B | en |
local.search.author | Young, M | en |
local.search.author | Harrop, K | en |
local.search.author | Brown, Judith Elizabeth | en |
local.uneassociation | Unknown | en |
local.year.published | 2004 | en |
Appears in Collections: | Journal Article |
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