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Title: Immunity to Helminth Infections
Contributor(s): Dineen, J K (author); Love, R J (author); Gregg, Peter (author)orcid ; Donald, A D (author); Anderson, N (author); Bremner, K C (author); Fridemanis, R (author); Kelly, J D (author); Rothwell, T L W (author); Jones, W O (author); Goodrich, B S (author); Smith, I D (author); Merritt, G C (author); Hogarth-Scott, R S (author); Curtain, C C (author)
Corporate Author: CSIRO
Publication Date: 1974
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Abstract: Vaccination with irradiated Trichostrongylus colubriformis larvae gave over 90% protection in mature sheep in pen studies, in which challenge with normal infective larvae was given either by impulse (a single large does of larvae) or sequentially (frequent smaller doses administered orally over a period of four weeks). Sequential challenge was designed to simulate the type of exposure to infective larvae likely to be encountered in the field. Vaccination was highly effective whether challenge infection was superimposed on the worm burden developed from the irradiated larvae or given after removal of the vaccine worm burden by anthelmintic treatment.
Publication Type: Book Chapter
Source of Publication: CSIRO Division of Animal Health 1974, v.1974, p. 75-83
Publisher: Sheils Printing
Place of Publication: Australia
Field of Research (FOR): 070205 Animal Protection (Pests and Pathogens)
HERDC Category Description: B2 Chapter in a Book - Other
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Series Name: CSIRO:Division of Animal Health
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Appears in Collections:Book Chapter
School of Environmental and Rural Science

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