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https://hdl.handle.net/1959.11/21271
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DC Field | Value | Language |
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dc.contributor.author | Gerber, Priscilla Freitas | en |
dc.contributor.author | Xiao, Chao-Ting | en |
dc.contributor.author | Chen, Qi | en |
dc.contributor.author | Zhang, Jianqiang | en |
dc.contributor.author | Halbur, Patrick G | en |
dc.contributor.author | Opriessnig, Tanja | en |
dc.date.accessioned | 2017-06-06T09:32:00Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Veterinary Microbiology, 174(1-2), p. 86-92 | en |
dc.identifier.issn | 1873-2542 | en |
dc.identifier.issn | 0378-1135 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/21271 | - |
dc.description.abstract | Porcine epidemic diarrhea virus (PEDV) is considered an emergent pathogen associated with high economic losses in many pig rearing areas. Recently it has been suggested that PEDV could be transmitted to naïve pig populations through inclusion of spray-dried porcine plasma (SDPP) into the nursery diet which led to a ban of SDPP in several areas in North America and Europe. To determine the effect of spray-drying on PEDV infectivity, 3-week-old pigs were intragastrically inoculated with (1) raw porcine plasma spiked with PEDV (RAW-PEDV-CONTROL), (2) porcine plasma spiked with PEDV and then spray dried (SD-PEDV-CONTROL), (3) raw plasma from PEDV infected pigs (RAW-SICK), (4) spray-dried plasma from PEDV infected pigs (SD-SICK), or (5) spray-dried plasma from PEDV negative pigs (SD-NEG-CONTROL). For the spray-drying process, a tabletop spray-dryer with industry-like settings for inlet and outlet temperatures was used. In the RAW-PEDV-CONTROL group, PEDV RNA was present in feces at day post infection (dpi) 3 and the pigs seroconverted by dpi 14. In contrast, PEDV RNA in feces was not detected in any of the pigs in the other groups including the SD-PEDV-CONTROL group and none of the pigs had seroconverted by termination of the project at dpi 28. This work provides direct evidence that the experimental spray-drying process used in this study was effective in inactivating infectious PEDV in the plasma. Additionally, plasma collected from PEDV infected pigs at peak disease did not contain infectious PEDV. These findings suggest that the risk for PEDV transmission through commercially produced SDPP is minimal. | en |
dc.language | en | en |
dc.publisher | Elsevier BV | en |
dc.relation.ispartof | Veterinary Microbiology | en |
dc.title | The spray-drying process is sufficient to inactivate infectious porcine epidemic diarrhea virus in plasma | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1016/j.vetmic.2014.09.008 | en |
dc.subject.keywords | Veterinary Virology | en |
dc.subject.keywords | Veterinary Medicine | en |
dc.subject.keywords | Veterinary Epidemiology | en |
local.contributor.firstname | Priscilla Freitas | en |
local.contributor.firstname | Chao-Ting | en |
local.contributor.firstname | Qi | en |
local.contributor.firstname | Jianqiang | en |
local.contributor.firstname | Patrick G | en |
local.contributor.firstname | Tanja | en |
local.subject.for2008 | 070704 Veterinary Epidemiology | en |
local.subject.for2008 | 070712 Veterinary Virology | en |
local.subject.for2008 | 070706 Veterinary Medicine | en |
local.subject.seo2008 | 830308 Pigs | en |
local.profile.school | School of Environmental and Rural Science | en |
local.profile.email | pgerber2@une.edu.au | en |
local.output.category | C1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-chute-20170602-153755 | en |
local.publisher.place | Netherlands | en |
local.format.startpage | 86 | en |
local.format.endpage | 92 | en |
local.identifier.scopusid | 84909966546 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 174 | en |
local.identifier.issue | 1-2 | en |
local.contributor.lastname | Gerber | en |
local.contributor.lastname | Xiao | en |
local.contributor.lastname | Chen | en |
local.contributor.lastname | Zhang | en |
local.contributor.lastname | Halbur | en |
local.contributor.lastname | Opriessnig | en |
dc.identifier.staff | une-id:pgerber2 | en |
local.profile.orcid | 0000-0002-8343-8299 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:21463 | en |
local.identifier.handle | https://hdl.handle.net/1959.11/21271 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | The spray-drying process is sufficient to inactivate infectious porcine epidemic diarrhea virus in plasma | en |
local.output.categorydescription | C1 Refereed Article in a Scholarly Journal | en |
local.search.author | Gerber, Priscilla Freitas | en |
local.search.author | Xiao, Chao-Ting | en |
local.search.author | Chen, Qi | en |
local.search.author | Zhang, Jianqiang | en |
local.search.author | Halbur, Patrick G | en |
local.search.author | Opriessnig, Tanja | en |
local.uneassociation | Unknown | en |
local.year.published | 2014 | en |
local.subject.for2020 | 300905 Veterinary epidemiology | en |
local.subject.for2020 | 300914 Veterinary virology | en |
local.subject.for2020 | 300907 Veterinary medicine (excl. urology) | en |
local.subject.seo2020 | 100410 Pigs | en |
Appears in Collections: | Journal Article |
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