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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/20596
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dc.contributor.authorAl Sheikha, Dimaen
dc.contributor.authorWilkinson, Brendanen
dc.contributor.authorSanthakumar, Gajanen
dc.contributor.authorThaysen-Andersen, Mortenen
dc.contributor.authorPayne, Richard Jen
dc.date.accessioned2017-04-28T12:25:00Z-
dc.date.issued2013-
dc.identifier.citationOrganic & Biomolecular Chemistry, 11(36), p. 6090-6096en
dc.identifier.issn1477-0539en
dc.identifier.issn1477-0520en
dc.identifier.urihttps://hdl.handle.net/1959.11/20596-
dc.description.abstractThe efficient synthesis of homogeneous MUC1 peptide oligomers using sequential ligation reactions in the N-to-C and C-to-N directions is reported. The bi-directional ligation strategy makes use of thioester formation via N → S acyl shift chemistry in combination with peptide ligation reactions and was used to prepare a library of peptide oligomers ranging in molecular mass from 3.8-9.4 kDa, comprised of between 2 and 5 repeats of the MUC1 variable number tandem repeat sequence.en
dc.languageenen
dc.publisherRoyal Society of Chemistryen
dc.relation.ispartofOrganic & Biomolecular Chemistryen
dc.titleSynthesis of homogeneous MUC1 oligomers via a bi-directional ligation strategyen
dc.typeJournal Articleen
dc.identifier.doi10.1039/c3ob41363ben
dc.subject.keywordsBiologically Active Moleculesen
dc.subject.keywordsProteins and Peptidesen
dc.subject.keywordsOrganic Chemical Synthesisen
local.contributor.firstnameDimaen
local.contributor.firstnameBrendanen
local.contributor.firstnameGajanen
local.contributor.firstnameMortenen
local.contributor.firstnameRichard Jen
local.subject.for2008030503 Organic Chemical Synthesisen
local.subject.for2008030401 Biologically Active Moleculesen
local.subject.for2008030406 Proteins and Peptidesen
local.subject.seo2008929999 Health not elsewhere classifieden
local.subject.seo2008970103 Expanding Knowledge in the Chemical Sciencesen
local.subject.seo2008970106 Expanding Knowledge in the Biological Sciencesen
local.profile.schoolSchool of Science and Technologyen
local.profile.emailbwilkin7@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20170323-11356en
local.publisher.placeUnited Kingdomen
local.format.startpage6090en
local.format.endpage6096en
local.identifier.scopusid84882978971en
local.peerreviewedYesen
local.identifier.volume11en
local.identifier.issue36en
local.contributor.lastnameAl Sheikhaen
local.contributor.lastnameWilkinsonen
local.contributor.lastnameSanthakumaren
local.contributor.lastnameThaysen-Andersenen
local.contributor.lastnamePayneen
dc.identifier.staffune-id:bwilkin7en
local.profile.orcid0000-0003-1866-6540en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:20790en
dc.identifier.academiclevelAcademicen
local.title.maintitleSynthesis of homogeneous MUC1 oligomers via a bi-directional ligation strategyen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorAl Sheikha, Dimaen
local.search.authorWilkinson, Brendanen
local.search.authorSanthakumar, Gajanen
local.search.authorThaysen-Andersen, Mortenen
local.search.authorPayne, Richard Jen
local.uneassociationUnknownen
local.year.published2013en
local.subject.for2020340401 Biologically active moleculesen
local.subject.for2020340503 Organic chemical synthesisen
local.subject.for2020340407 Proteins and peptidesen
local.subject.seo2020280105 Expanding knowledge in the chemical sciencesen
local.subject.seo2020280102 Expanding knowledge in the biological sciencesen
local.codeupdate.date2022-02-13T16:39:49.108en
local.codeupdate.epersonbwilkin7@une.edu.auen
local.codeupdate.finalisedtrueen
local.original.for2020340401 Biologically active moleculesen
local.original.for2020340407 Proteins and peptidesen
local.original.for2020340503 Organic chemical synthesisen
local.original.seo2020280105 Expanding knowledge in the chemical sciencesen
local.original.seo2020280102 Expanding knowledge in the biological sciencesen
local.original.seo2020undefineden
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