Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/17813
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dc.contributor.authorJiang, Yuen
dc.contributor.authorXie, Minen
dc.contributor.authorStanton, Jo-Annen
dc.contributor.authorBrauning, Rudigeren
dc.contributor.authorBarris, Wesley Cen
dc.contributor.authorHourlier, Thibauten
dc.contributor.authorAken, Bronwen Len
dc.contributor.authorSearle, Stephen M Jen
dc.contributor.authorAdelson, David Len
dc.contributor.authorBian, Chaoen
dc.contributor.authorCam, Graham Ren
dc.contributor.authorChen, Yulinen
dc.contributor.authorChen, Wenbinen
dc.contributor.authorCheng, Shifengen
dc.contributor.authorDeSilva, Udayaen
dc.contributor.authorDixen, Karenen
dc.contributor.authorDong, Yangen
dc.contributor.authorFan, Guangyien
dc.contributor.authorFranklin, Ian Ren
dc.contributor.authorFu, Shaoyinen
dc.contributor.authorFuentes-Utrilla, Pabloen
dc.contributor.authorGuan, Ruien
dc.contributor.authorHighland, Margaret Aen
dc.contributor.authorTalbot, Richarden
dc.contributor.authorHolder, Michael Een
dc.contributor.authorHuang, Guodongen
dc.contributor.authorIngham, Aaron Ben
dc.contributor.authorJhangiani, Shalini Nen
dc.contributor.authorKalra, Divyaen
dc.contributor.authorKovar, Christie Len
dc.contributor.authorLee, Sandraen
dc.contributor.authorLiu, Weiqingen
dc.contributor.authorLiu, Xinen
dc.contributor.authorLu, Changxinen
dc.contributor.authorMaddox, Jillian Fen
dc.contributor.authorLv, Tianen
dc.contributor.authorMathew, Tittuen
dc.contributor.authorMcWilliam, Seanen
dc.contributor.authorMenzies, Moiraen
dc.contributor.authorPan, Shengkaien
dc.contributor.authorRobelin, Daviden
dc.contributor.authorServin, Bertranden
dc.contributor.authorTownley, Daviden
dc.contributor.authorWang, Wenliangen
dc.contributor.authorWei, Binen
dc.contributor.authorFaraut, Thomasen
dc.contributor.authorWhite, Stephen Nen
dc.contributor.authorYang, Xinhuaen
dc.contributor.authorYe, Chenen
dc.contributor.authorYue, Yaojingen
dc.contributor.authorZeng, Pengen
dc.contributor.authorZhou, Qingen
dc.contributor.authorHansen, Jacob Ben
dc.contributor.authorKristiansen, Karstenen
dc.contributor.authorGibbs, Richard Aen
dc.contributor.authorFlicek, Paulen
dc.contributor.authorWu, Chunhuaen
dc.contributor.authorWarkup, Christopher Cen
dc.contributor.authorJones, Huw Een
dc.contributor.authorOddy, Huttonen
dc.contributor.authorNicholas, Frank Wen
dc.contributor.authorMcEwan, John Cen
dc.contributor.authorKijas, James Wen
dc.contributor.authorWang, Junen
dc.contributor.authorWorley, Kim Cen
dc.contributor.authorArchibald, Alan Len
dc.contributor.authorCockett, Noelleen
dc.contributor.authorMuzny, Donna Men
dc.contributor.authorXu, Xunen
dc.contributor.authorWang, Wenen
dc.contributor.authorDalrymple, Brian Pen
dc.contributor.authorLi, Yuxiangen
dc.contributor.authorZhang, Wenguangen
dc.date.accessioned2015-08-13T14:33:00Z-
dc.date.issued2014-
dc.identifier.citationScience, 344(6188), p. 1168-1173en
dc.identifier.issn1095-9203en
dc.identifier.issn0036-8075en
dc.identifier.urihttps://hdl.handle.net/1959.11/17813-
dc.description.abstractSheep ('Ovis aries') are a major source of meat, milk, and fiber in the form of wool and represent a distinct class of animals that have a specialized digestive organ, the rumen, that carries out the initial digestion of plant material. We have developed and analyzed a high-quality reference sheep genome and transcriptomes from 40 different tissues. We identified highly expressed genes encoding keratin cross-linking proteins associated with rumen evolution. We also identified genes involved in lipid metabolism that had been amplified and/or had altered tissue expression patterns. This may be in response to changes in the barrier lipids of the skin, an interaction between lipid metabolism and wool synthesis, and an increased role of volatile fatty acids in ruminants compared with nonruminant animals.en
dc.languageenen
dc.publisherAmerican Association for the Advancement of Science (AAAS)en
dc.relation.ispartofScienceen
dc.titleThe sheep genome illuminates biology of the rumen and lipid metabolismen
dc.typeJournal Articleen
dc.identifier.doi10.1126/science.1252806en
dcterms.accessRightsGreenen
dc.subject.keywordsAnimal Nutritionen
dc.subject.keywordsAnimal Growth and Developmenten
dc.subject.keywordsAnimal Breedingen
local.contributor.firstnameYuen
local.contributor.firstnameMinen
local.contributor.firstnameJo-Annen
local.contributor.firstnameRudigeren
local.contributor.firstnameWesley Cen
local.contributor.firstnameThibauten
local.contributor.firstnameBronwen Len
local.contributor.firstnameStephen M Jen
local.contributor.firstnameDavid Len
local.contributor.firstnameChaoen
local.contributor.firstnameGraham Ren
local.contributor.firstnameYulinen
local.contributor.firstnameWenbinen
local.contributor.firstnameShifengen
local.contributor.firstnameUdayaen
local.contributor.firstnameKarenen
local.contributor.firstnameYangen
local.contributor.firstnameGuangyien
local.contributor.firstnameIan Ren
local.contributor.firstnameShaoyinen
local.contributor.firstnamePabloen
local.contributor.firstnameRuien
local.contributor.firstnameMargaret Aen
local.contributor.firstnameRicharden
local.contributor.firstnameMichael Een
local.contributor.firstnameGuodongen
local.contributor.firstnameAaron Ben
local.contributor.firstnameShalini Nen
local.contributor.firstnameDivyaen
local.contributor.firstnameChristie Len
local.contributor.firstnameSandraen
local.contributor.firstnameWeiqingen
local.contributor.firstnameXinen
local.contributor.firstnameChangxinen
local.contributor.firstnameJillian Fen
local.contributor.firstnameTianen
local.contributor.firstnameTittuen
local.contributor.firstnameSeanen
local.contributor.firstnameMoiraen
local.contributor.firstnameShengkaien
local.contributor.firstnameDaviden
local.contributor.firstnameBertranden
local.contributor.firstnameDaviden
local.contributor.firstnameWenliangen
local.contributor.firstnameBinen
local.contributor.firstnameThomasen
local.contributor.firstnameStephen Nen
local.contributor.firstnameXinhuaen
local.contributor.firstnameChenen
local.contributor.firstnameYaojingen
local.contributor.firstnamePengen
local.contributor.firstnameQingen
local.contributor.firstnameJacob Ben
local.contributor.firstnameKarstenen
local.contributor.firstnameRichard Aen
local.contributor.firstnamePaulen
local.contributor.firstnameChunhuaen
local.contributor.firstnameChristopher Cen
local.contributor.firstnameHuw Een
local.contributor.firstnameHuttonen
local.contributor.firstnameFrank Wen
local.contributor.firstnameJohn Cen
local.contributor.firstnameJames Wen
local.contributor.firstnameJunen
local.contributor.firstnameKim Cen
local.contributor.firstnameAlan Len
local.contributor.firstnameNoelleen
local.contributor.firstnameDonna Men
local.contributor.firstnameXunen
local.contributor.firstnameWenen
local.contributor.firstnameBrian Pen
local.contributor.firstnameYuxiangen
local.contributor.firstnameWenguangen
local.subject.for2008070201 Animal Breedingen
local.subject.for2008070202 Animal Growth and Developmenten
local.subject.for2008070204 Animal Nutritionen
local.subject.seo2008970106 Expanding Knowledge in the Biological Sciencesen
local.subject.seo2008830311 Sheep - Woolen
local.subject.seo2008830310 Sheep - Meaten
local.profile.schoolState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China, Commonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, College of Animal Science and Technology, Northwest AandF University, Yangling 712100, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolDepartment of Anatomy, University of Otago, Dunedin 9054, New Zealanden
local.profile.schoolAgResearch, Invermay Agricultural Centre, Mosgiel 9053, New Zealanden
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, Cobb-Vantress, Siloam Springs, AR 72761, United Statesen
local.profile.schoolWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdomen
local.profile.schoolWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdomen
local.profile.schoolWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdomen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, School of Molecular and Biomedical Science, University of Adelaide, Adelaide, SA 5005, Australiaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, Genomic Strategies, Post Office Box 123, Lawson, NSW 2783, Australiaen
local.profile.schoolCollege of Animal Science and Technology, Northwest AandF University, Yangling 712100, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, Department of Animal Science, Oklahoma State University, Stillwater, OK 74078, United Statesen
local.profile.schoolDepartment of Biology, University of Copenhagen, DK-2100 Copenhagen Ø, Denmarken
local.profile.schoolState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, 11 Fourth Road, Belair, SA 5052, Australiaen
local.profile.schoolInner Mongolia Agricultural University, Hohhot 010018, Chinaen
local.profile.schoolEdiburgh Genomics, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdomen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolU.S. Department of Agriculture Agricultural Research Service Animal Disease Research Unit, Pullman, WA 99164, United States, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, United Statesen
local.profile.schoolEdiburgh Genomics, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdomen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australiaen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolUtah State University, Logan, UT 84322-4815, United States, 16 Park Square, Port Melbourne, VIC 3207, Australiaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australiaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australiaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolInstitut National de la Recherche Agronomique, Laboratoire de Génétique Cellulaire, UMR 444, Castanet-Tolosan F-31326, Franceen
local.profile.schoolInstitut National de la Recherche Agronomique, Laboratoire de Génétique Cellulaire, UMR 444, Castanet-Tolosan F-31326, Franceen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australia, Illumina Cambridge Ltd., Chesterford Research Park, Saffron Walden CB10 1XL, United Kingdomen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolInstitut National de la Recherche Agronomique, Laboratoire de Génétique Cellulaire, UMR 444, Castanet-Tolosan F-31326, Franceen
local.profile.schoolU.S. Department of Agriculture Agricultural Research Service Animal Disease Research Unit, Pullman, WA 99164, United States, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, United Statesen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolLanzhou Institute of Husbandry and Pharmaceutical Science, Lanzhou, 730050, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolDepartment of Biology, University of Copenhagen, DK-2100 Copenhagen Ø, Denmarken
local.profile.schoolDepartment of Biology, University of Copenhagen, DK-2200 Copenhagen N, Denmarken
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdomen
local.profile.schoolUtah State University, Logan, UT 84322-1435, United States, Huntsman Cancer Institute, Salt Lake City, UT 84112, United Statesen
local.profile.schoolBiosciences Knowledge Transfer Network, Roslin Institute, Easter Bush, Midlothian, EH25 9RG, United Kingdomen
local.profile.schoolBiosciences Knowledge Transfer Network, Roslin Institute, Easter Bush, Midlothian, EH25 9RG, United Kingdomen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolFaculty of Veterinary Science, University of Sydney, NSW 2006, Australiaen
local.profile.schoolAgResearch, Invermay Agricultural Centre, Mosgiel 9053, New Zealanden
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australiaen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolRoslin Institute and Royal (Dick), School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdomen
local.profile.schoolUtah State University, Logan, UT 84322-1435, United Statesen
local.profile.schoolHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, United Statesen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Chinaen
local.profile.schoolCommonwealth Scientific and Industrial Research Organisation Animal Food and Health Sciences, St Lucia, QLD 4067, Australiaen
local.profile.schoolBGI-Shenzhen, Shenzhen 518083, Chinaen
local.profile.schoolState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China, Inner Mongolia Agricultural University, Hohhot 010018, China, Institute of ATCG, Nei Mongol Bio-Information, Hohhot, Chinaen
local.profile.emailhwei3@une.edu.auen
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local.output.categoryC1en
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local.record.institutionUniversity of New Englanden
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local.publisher.placeUnited States of Americaen
local.format.startpage1168en
local.format.endpage1173en
local.identifier.scopusid84901852226en
local.url.openhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157056en
local.peerreviewedYesen
local.identifier.volume344en
local.identifier.issue6188en
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local.contributor.lastnameJiangen
local.contributor.lastnameXieen
local.contributor.lastnameStantonen
local.contributor.lastnameBrauningen
local.contributor.lastnameBarrisen
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local.contributor.lastnameChenen
local.contributor.lastnameChenen
local.contributor.lastnameChengen
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local.contributor.lastnameDixenen
local.contributor.lastnameDongen
local.contributor.lastnameFanen
local.contributor.lastnameFranklinen
local.contributor.lastnameFuen
local.contributor.lastnameFuentes-Utrillaen
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local.contributor.lastnameDalrympleen
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local.identifier.unepublicationidune:18024en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleThe sheep genome illuminates biology of the rumen and lipid metabolismen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorJiang, Yuen
local.search.authorXie, Minen
local.search.authorStanton, Jo-Annen
local.search.authorBrauning, Rudigeren
local.search.authorBarris, Wesley Cen
local.search.authorHourlier, Thibauten
local.search.authorAken, Bronwen Len
local.search.authorSearle, Stephen M Jen
local.search.authorAdelson, David Len
local.search.authorBian, Chaoen
local.search.authorCam, Graham Ren
local.search.authorChen, Yulinen
local.search.authorChen, Wenbinen
local.search.authorCheng, Shifengen
local.search.authorDeSilva, Udayaen
local.search.authorDixen, Karenen
local.search.authorDong, Yangen
local.search.authorFan, Guangyien
local.search.authorFranklin, Ian Ren
local.search.authorFu, Shaoyinen
local.search.authorFuentes-Utrilla, Pabloen
local.search.authorGuan, Ruien
local.search.authorHighland, Margaret Aen
local.search.authorTalbot, Richarden
local.search.authorHolder, Michael Een
local.search.authorHuang, Guodongen
local.search.authorIngham, Aaron Ben
local.search.authorJhangiani, Shalini Nen
local.search.authorKalra, Divyaen
local.search.authorKovar, Christie Len
local.search.authorLee, Sandraen
local.search.authorLiu, Weiqingen
local.search.authorLiu, Xinen
local.search.authorLu, Changxinen
local.search.authorMaddox, Jillian Fen
local.search.authorLv, Tianen
local.search.authorMathew, Tittuen
local.search.authorMcWilliam, Seanen
local.search.authorMenzies, Moiraen
local.search.authorPan, Shengkaien
local.search.authorRobelin, Daviden
local.search.authorServin, Bertranden
local.search.authorTownley, Daviden
local.search.authorWang, Wenliangen
local.search.authorWei, Binen
local.search.authorFaraut, Thomasen
local.search.authorWhite, Stephen Nen
local.search.authorYang, Xinhuaen
local.search.authorYe, Chenen
local.search.authorYue, Yaojingen
local.search.authorZeng, Pengen
local.search.authorZhou, Qingen
local.search.authorHansen, Jacob Ben
local.search.authorKristiansen, Karstenen
local.search.authorGibbs, Richard Aen
local.search.authorFlicek, Paulen
local.search.authorWu, Chunhuaen
local.search.authorWarkup, Christopher Cen
local.search.authorJones, Huw Een
local.search.authorOddy, Huttonen
local.search.authorNicholas, Frank Wen
local.search.authorMcEwan, John Cen
local.search.authorKijas, James Wen
local.search.authorWang, Junen
local.search.authorWorley, Kim Cen
local.search.authorArchibald, Alan Len
local.search.authorCockett, Noelleen
local.search.authorMuzny, Donna Men
local.search.authorXu, Xunen
local.search.authorWang, Wenen
local.search.authorDalrymple, Brian Pen
local.search.authorLi, Yuxiangen
local.search.authorZhang, Wenguangen
local.uneassociationUnknownen
local.identifier.wosid000336791200050en
local.year.published2014en
local.subject.for2020300305 Animal reproduction and breedingen
local.subject.for2020300301 Animal growth and developmenten
local.subject.for2020300303 Animal nutritionen
local.subject.seo2020280102 Expanding knowledge in the biological sciencesen
local.subject.seo2020100413 Sheep for woolen
local.subject.seo2020100412 Sheep for meaten
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