Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/15529
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dc.contributor.authorPorto-Neto, L Ren
dc.contributor.authorLee, S Hen
dc.contributor.authorSonstegard, T Sen
dc.contributor.authorVan Tassell, C Pen
dc.contributor.authorLee, H Ken
dc.contributor.authorGibson, Johnen
dc.contributor.authorGondro, Cedricen
dc.date.accessioned2014-08-26T14:28:00Z-
dc.date.issued2014-
dc.identifier.citationAnimal Genetics, 45(2), p. 180-190en
dc.identifier.issn1365-2052en
dc.identifier.issn0268-9146en
dc.identifier.urihttps://hdl.handle.net/1959.11/15529-
dc.description.abstractThe Korean Hanwoo cattle have been intensively selected for production traits, especially high intramuscular fat content. It is believed that ancient crossings between different breeds contributed to forming the Hanwoo, but little is known about the genomic differences and similarities between other cattle breeds and the Hanwoo. In this work, cattle breeds were grouped by origin into four types and used for comparisons: the Europeans (represented by six breeds), zebu (Nelore), African taurine (N'Dama) and Hanwoo. All animals had genotypes for around 680 000 SNPs after quality control of genotypes. Average heterozygosity was lower in Nelore and N'Dama (0.22 and 0.21 respectively) than in Europeans (0.26–0.31, with Shorthorn as outlier at 0.24) and Hanwoo (0.29). Pairwise FST analyses demonstrated that Hanwoo are more related to European cattle than to Nelore, with N'Dama in an intermediate position. This finding was corroborated by principal components and unsupervised hierarchical clustering. Using genome-wide smoothed FST, 55 genomic regions potentially under positive selection in Hanwoo were identified. Among these, 29 were regions also detected in previous studies. Twenty-four regions were exclusive to Hanwoo, and a number of other regions were shared with one or two of the other groups. These regions overlap a number of genes that are related to immune, reproduction and fatty acid metabolism pathways. Further analyses are needed to better characterize the ancestry of the Hanwoo cattle and to define the genes responsible to the identified selection peaks.en
dc.languageenen
dc.publisherWiley-Blackwell Publishing Ltden
dc.relation.ispartofAnimal Geneticsen
dc.titleGenome-wide Detection of Signatures of Selection in Korean Hanwoo Cattleen
dc.typeJournal Articleen
dc.identifier.doi10.1111/age.12119en
dc.subject.keywordsPopulation, Ecological and Evolutionary Geneticsen
local.contributor.firstnameL Ren
local.contributor.firstnameS Hen
local.contributor.firstnameT Sen
local.contributor.firstnameC Pen
local.contributor.firstnameH Ken
local.contributor.firstnameJohnen
local.contributor.firstnameCedricen
local.subject.for2008060411 Population, Ecological and Evolutionary Geneticsen
local.subject.seo2008970106 Expanding Knowledge in the Biological Sciencesen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailjgibson5@une.edu.auen
local.profile.emailcgondro2@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20140618-16165en
local.publisher.placeUnited Kingdomen
local.format.startpage180en
local.format.endpage190en
local.peerreviewedYesen
local.identifier.volume45en
local.identifier.issue2en
local.contributor.lastnamePorto-Netoen
local.contributor.lastnameLeeen
local.contributor.lastnameSonstegarden
local.contributor.lastnameVan Tassellen
local.contributor.lastnameLeeen
local.contributor.lastnameGibsonen
local.contributor.lastnameGondroen
dc.identifier.staffune-id:jgibson5en
dc.identifier.staffune-id:cgondro2en
local.profile.orcid0000-0003-0666-656Xen
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:15762en
local.identifier.handlehttps://hdl.handle.net/1959.11/15529en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleGenome-wide Detection of Signatures of Selection in Korean Hanwoo Cattleen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorPorto-Neto, L Ren
local.search.authorLee, S Hen
local.search.authorSonstegard, T Sen
local.search.authorVan Tassell, C Pen
local.search.authorLee, H Ken
local.search.authorGibson, Johnen
local.search.authorGondro, Cedricen
local.uneassociationUnknownen
local.identifier.wosid000332140000003en
local.year.published2014en
local.subject.for2020310599 Genetics not elsewhere classifieden
local.subject.seo2020280102 Expanding knowledge in the biological sciencesen
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