Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/11748
Title: | The procine gonadotropin-releasing hormone receptor gene (GNRHR): Genomic organization, polymorphisms, and association with the number of corpora lutea | Contributor(s): | Jiang, Z (author); Gibson, John Paul (author); Archibald, AL (author); Haley, CS (author) | Publication Date: | 2001 | Handle Link: | https://hdl.handle.net/1959.11/11748 | Abstract: | The interaction of gonadotropin-releasing hormone (GNRH) and its receptor (GNRHR) is critical in the endocrine regulation of reproduction. The gene (GNRHR) encoding the receptor has been mapped to porcine chromosome 8. There is evidence for three quantitative trait loci (QTL) influencing ovulation rate on this chromosome. We obtained an almost complete sequence (3993 bp, excluding intron 1) of the porcine GNRHR gene using PCR-based comparative genomic walking and inverse genomic walking approaches. Twelve polymorphisms were detected by sequencing of pooled DNA of Chinese Taihu and European Large White pigs, including 7 base substitutions and 5 insertions-deletions (indels). A F₂ population of Meishan x European Large White pigs was genotyped for a TG indel in the promoter region, and a C/G substitution in the 3' UTR (untranslated region). A significant association of the C/G substitution with number of corpora lutea at first parity was observed. | Publication Type: | Journal Article | Source of Publication: | Genome, 44(1), p. 7-12 | Publisher: | NRC Research Press | Place of Publication: | Canada | ISSN: | 1480-3321 0831-2796 |
Fields of Research (FoR) 2008: | 070201 Animal Breeding | Socio-Economic Objective (SEO) 2008: | 830301 Beef Cattle | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Publisher/associated links: | http://www.nrcresearchpress.com/doi/abs/10.1139/g00-083 |
---|---|
Appears in Collections: | Journal Article |
Files in This Item:
File | Description | Size | Format |
---|
Page view(s)
1,046
checked on Mar 31, 2024
Download(s)
2
checked on Mar 31, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.