This thesis explores how trust is enacted and sustained in leader–follower relationships within Australian not-for-profit human services organisations. Using qualitative interviews with 34 participants across six organisations, it examines trust as a relational practice shaped by delegation, openness, and vulnerability. Followers respond with autonomy, responsibility, and values-driven initiative, reinforcing organisational culture. The concept of Professional Intimacy, an ethical closeness grounded in shared purpose, emerges as key to deepening trust and accountability. Findings highlight trust as both a leadership and followership practice, central to identity, motivation, and cultural continuity. This study contributes a situated understanding of trust as dynamic, reciprocal, and vital to mission-driven organisational life.

Objective

This systematic review evaluates the therapeutic potential of quercetin (QUE) and resveratrol (RSV) in Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS), focusing on their effects on glymphatic function, cerebrospinal fluid (CSF) dynamics, neuroglial health, and blood–brain barrier (BBB) permeability.

Methods

A systematic search was conducted across PubMed, ScienceDirect, and ProQuest following PRISMA guidelines for studies published between 2019 and 2024. Thirty-six studies, including experimental models and clinical trials, were identified and assessed for outcomes relating to antioxidant, anti-inflammatory, and neuroprotective effects of QUE and RSV.

Results

Across 56 studies, both QUE and RSV significantly enhanced antioxidant defences (upregulation of SOD, GSH, GPx, CAT) and downregulated pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, NF-κB). Several studies also reported Nrf2/HO-1 and SIRT1/AMPK activation. BBB integrity improved via increased claudin‑5/occludin/ZO‑1 expression and reduced Evans blue/sodium fluorescein extravasation; cerebrovascular reactivity and cerebral blood flow (CBF) were frequently restored. Glymphatic outcomes demonstrated enhanced AQP4 polarization at end feet and accelerated clearance of fluorescent tracers and β-amyloid in vivo, with preserved astrocyte–pericyte coupling. Neuroglial health improved (reduced microglial M1 markers, increased M2/Arg‑1 and astrocytic homeostatic markers), alongside neuronal survival and synaptic proteins. Nanoparticle/liposomal formulations of QUE/RSV increased BBB penetration and brain concentrations relative to free compounds.

Conclusion

QUE and RSV demonstrate significant potential as adjunctive therapies for mitigating neuroinflammation, oxidative stress, and neurodegenerative progression through glymphatic and BBB modulation. However, further high-quality, long-term clinical trials are needed to validate these findings, optimise delivery systems, and establish translational relevance to human neurodegenerative conditions.

There are three sexual fluids from women: lubrication (e.g. transudation of fluid across the mucosa of the vagina, and mucus from the greater vestibular glands); female ejaculation (from paraurethral glands); and gushing. Orthodox western medicine and physiology does not yet have a standardized description or explanation for the third, gushing. The present paper proposes that the gushing fluid is a filtrate of plasma, produced by the mechanism known as transudation. This is an additional application for the transudation mechanism, after the well accepted roles in lubrication of the vagina, and in generating serous fluids. The present model proposes that the fluid released in a gush arises from the ventral wall of the vagina due to the presence there of increased surface area of mucosa, dilated arterioles, pressurized venous and lymphatic plexuses, and compression provided by muscle contraction during orgasm.

Ground-based readings of temperature and rainfall, satellite imagery, aerial photographs, ground verification data and Digital Elevation Model (DEM) were used in this study. Ground-based meteorological information was obtained from Bangladesh Meteorological Department (BMD) for the period 1977 to 2015 and was used to determine the trends of rainfall and temperature in this thesis. Satellite images obtained from the US Geological Survey (USGS) Center for Earth Resources Observation and Science (EROS) website (www.glovis.usgs.gov) in four time periods were analysed to assess the dynamics of mangrove population at species level. Remote sensing techniques, as a solution to lack of spatial data at a relevant scale and difficulty in accessing the mangroves for field survey and also as an alternative to the traditional methods were used in monitoring of the changes in mangrove species composition, . To identify mangrove forests, a number of satellite sensors have been used, including Landsat TM/ETM/OLI, SPOT, CBERS, SIR, ASTER, and IKONOS and Quick Bird. The use of conventional medium-resolution remote sensor data (e.g., Landsat TM, ASTER, SPOT) in the identification of different mangrove species remains a challenging task. In many developing countries, the high cost of acquiring high- resolution satellite imagery excludes its routine use. The free availability of archived images enables the development of useful techniques in its use and therefor Landsat imagery were used in this study for mangrove species classification. Satellite imagery used in this study includes: Landsat Multispectral Scanner (MSS) of 57 m resolution acquired on 1st February 1977, Landsat Thematic Mapper (TM) of 28.5 m resolution acquired on 5th February 1989, Landsat Enhanced Thematic Mapper (ETM+) of 28.5 m resolution acquired on 28th February 2000 and Landsat Operational Land Imager (OLI) of 30 m resolution acquired on 4th February 2015. To study tidal channel dynamics of the study area, aerial photographs from 1974 and 2011, and a satellite image from 2017 were used. Satellite images from 1974 with good spatial resolution of the area were not available, and therefore aerial photographs of comparatively high and fine resolution were considered adequate to obtain information on tidal channel dynamics. Although high-resolution satellite imagery was available for 2011, aerial photographs were used for this study due to their effectiveness in terms of cost and also ease of comparison with the 1974 photographs. The aerial photographs were sourced from the Survey of Bangladesh (SOB). The Sentinel-2 satellite image from 2017 was downloaded from the European Space Agency (ESA) website (https://scihub.copernicus.eu/). In this research, elevation data acts as the main parameter in the determination of the sea level rise (SLR) impacts on the spatial distribution of the future mangrove species of the Bangladesh Sundarbans. High resolution elevation data is essential for this kind of research where every centimeter counts due to the low-lying characteristics of the study area. The high resolution (less than 1m vertical error) DEM data used in this study was obtained from Water Resources Planning Organization (WRPO), Bangladesh. The elevation information used to construct the DEM was originally collected by a Finnish consulting firm known as FINNMAP in 1991 for the Bangladesh government.

Previous research shows that reinforcement of variable responding will facilitate sequence learning in rats (Neuringer, Deiss & Olson, 2000) but may interfere with sequence learning in humans (Maes & van der Goot, 2006). The present study aimed to replicate and extend previous research by assessing the role of behavioral variability in the learning of difficult target sequences across 3 species: humans (n = 60), hens (n = 18) and possums (n = 6). Participants were randomly allocated to one of three experimental conditions (Control, Variable, Any). In the Control conditions sequences were only reinforced if they were the target sequence, in the Variability conditions sequences were concurrently reinforced on a Variable Interval 60-s schedule if the just entered sequence met a variability criterion, and in the Any condition sequences were concurrently reinforced on a Variable Interval 60-s schedule for any sequence entered. The results support previous findings with animals and humans; hens and possums were more likely to learn the target sequence in the Variability condition, and human participants were more likely to learn the target sequence in the Control condition. Possible explanations for differences between the performance of humans and animals on this task will be discussed.

This dataset provides all the raw and analysed data for the thesis titled 'The drivers and consequences of change to the physical character of waterholes on an Australian dryland river'.
The data has been divided into four folders that are aligned with the data chapters for the thesis. These being: (Ch 2) waterhole mapping, (Ch 3) floodplain gullies, (Ch 4) sediment transport and (Ch 5) fish.
A README file is provided for each chapter which contains a description of the individual datasets and a list of files that make up each dataset.
The data in this archive is a combination of data obtained from desktop studies as well as field work on the Darling River (i.e., the fish data).
Further, fish data were collected on the Darling River between Bourke and Wilcannia. Waterhole mapping was undertaken on the Barwon-Darling between Walgett and Wilcannia. Gully mapping was undertaken on the Barwon-Darling River between Mungindi and Wilcannia. Sediment transport capacity was assessed at five sites between Collarenebri and Tilpa.