Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/9812
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dc.contributor.authorChen, Yizhouen
dc.contributor.authorPiper, Een
dc.contributor.authorZhang, Yuandanen
dc.contributor.authorTier, Bruceen
dc.contributor.authorGraser, Hans-Ulrichen
dc.contributor.authorLuxford, B Gen
dc.contributor.authorMoran, Cen
dc.date.accessioned2012-03-23T14:07:00Z-
dc.date.issued2011-
dc.identifier.citationAnimal Genetics, 42(2), p. 219-221en
dc.identifier.issn1365-2052en
dc.identifier.issn0268-9146en
dc.identifier.urihttps://hdl.handle.net/1959.11/9812-
dc.description.abstractFeed efficiency and growth are the most important traits in pig production, and very few genetic markers have been reported to be associated with feed efficiency. The suppressor of cytokine signalling-2 (encoded by SOCS2) is the main negative regulator of somatic growth, and the knockout of SOCS2 and naturally mutant mice have high-growth phenotypes. Porcine SOCS2 was selected as a primary positional candidate for feed efficiency, because it is located on chromosome 5q, in the vicinity of a Quantitative Trait Locus (QTL) region for food conversion ratio in pigs. Here, we report five single nucleotide polymorphisms identified by sequencing of the promoter region and exon 1. One PCR-RFLP assay was designed for genotyping the polymorphism c.1667A > G (GenBank Accession No AY312266). Association analyses were performed in an Australian mapping resource pedigree population (PRDC-US43) for food conversion ratio, backfat, IGF1 level and growth traits and showed significant effects on average daily gain on test (ADG2) (P < 0.01) and marginal association with food conversion ratio (FCR) (P < 0.08).en
dc.languageenen
dc.publisherWiley-Blackwell Publishing Ltden
dc.relation.ispartofAnimal Geneticsen
dc.titleA single nucleotide polymorphism in suppressor of cytokine signalling-2 is associated with growth and feed conversion efficiency in pigsen
dc.typeJournal Articleen
dc.identifier.doi10.1111/j.1365-2052.2010.02107.xen
dc.subject.keywordsAnimal Breedingen
dc.subject.keywordsQuantitative Genetics (incl Disease and Trait Mapping Genetics)en
local.contributor.firstnameYizhouen
local.contributor.firstnameEen
local.contributor.firstnameYuandanen
local.contributor.firstnameBruceen
local.contributor.firstnameHans-Ulrichen
local.contributor.firstnameB Gen
local.contributor.firstnameCen
local.subject.for2008070201 Animal Breedingen
local.subject.for2008060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics)en
local.subject.seo2008830308 Pigsen
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.emailyizhou.chen@industry.nsw.gov.auen
local.profile.emailyzhang4@une.edu.auen
local.profile.emailbtier@une.edu.auen
local.profile.emailhgraser@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20120228-15589en
local.publisher.placeUnited Kingdomen
local.format.startpage219en
local.format.endpage221en
local.identifier.scopusid79952604412en
local.peerreviewedYesen
local.identifier.volume42en
local.identifier.issue2en
local.contributor.lastnameChenen
local.contributor.lastnamePiperen
local.contributor.lastnameZhangen
local.contributor.lastnameTieren
local.contributor.lastnameGraseren
local.contributor.lastnameLuxforden
local.contributor.lastnameMoranen
dc.identifier.staffune-id:ychen35en
dc.identifier.staffune-id:yzhang4en
dc.identifier.staffune-id:btieren
dc.identifier.staffune-id:hgraseren
local.profile.orcid0000-0002-1998-3313en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:10003en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleA single nucleotide polymorphism in suppressor of cytokine signalling-2 is associated with growth and feed conversion efficiency in pigsen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorChen, Yizhouen
local.search.authorPiper, Een
local.search.authorZhang, Yuandanen
local.search.authorTier, Bruceen
local.search.authorGraser, Hans-Ulrichen
local.search.authorLuxford, B Gen
local.search.authorMoran, Cen
local.uneassociationUnknownen
local.identifier.wosid000288219500013en
local.year.published2011en
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Journal Article
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