Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/9060
Title: | Variation in protein abundance profiles in the 'M. semitendinosus' of lambs bred from sires selected on the basis of growth and muscling potential | Contributor(s): | McDonagh, M B (author); Ferguson, K L (author); Bacic, A (author); Gardner, Graham E (author); Hegarty, Roger (author) | Publication Date: | 2006 | DOI: | 10.1071/AR04277 | Handle Link: | https://hdl.handle.net/1959.11/9060 | Abstract: | Relative abundance of proteins localised in the nuclear-enriched, total cell membrane and cytosolic fractions of the 'semitendinosus' muscle was compared between lambs bred from control (C), high muscling (M), and high growth rate (G) sires. In total, 31 proteins were identified whose abundance was differentially regulated between sire type. Differences in hind-limb muscle development between M lambs and C and G lambs were reflected in levels of proteins that regulate or function in cellular mechanisms of protein and energy metabolism. Despite no apparent difference in hind-limb muscle growth in G lambs compared to C, G lambs exhibited marked differences in proteins involved in regulation and function of energy metabolism. These results detail pathways that can be specifically targeted to enhance muscle accretion and growth in lambs. The development of means to manipulate these cellular mechanisms may yield greater gains in muscle accretion and growth rate than breeding on the basis for genetic capacity alone. | Publication Type: | Journal Article | Source of Publication: | Australian Journal of Agricultural Research, 57(6), p. 671-682 | Publisher: | CSIRO Publishing | Place of Publication: | Australia | ISSN: | 1444-9838 0004-9409 1836-5795 1836-0947 |
Fields of Research (FoR) 2008: | 070202 Animal Growth and Development | Socio-Economic Objective (SEO) 2008: | 830310 Sheep - Meat | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
---|---|
Appears in Collections: | Journal Article School of Environmental and Rural Science |
Files in This Item:
File | Description | Size | Format |
---|
SCOPUSTM
Citations
5
checked on Mar 16, 2024
Page view(s)
936
checked on Mar 7, 2023
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.