Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/8319
Title: Long chain omega-3 polyunsaturated fatty acids in the treatment of psychiatric illnesses in children and adolescents
Contributor(s): Clayton, EH (author); Hanstock, Tanya (author); Garg, ML (author); Hazell, PL (author)
Publication Date: 2007
DOI: 10.1111/j.1601-5215.2007.00189.x
Handle Link: https://hdl.handle.net/1959.11/8319
Abstract: Objective:  Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adolescents. Methods:  A search of Psychlit, PubMed and Cochrane Databases was conducted using the terms child, adolescent, bipolar, depression, psychosis, first-episode psychosis, schizophrenia, attention deficit hyperactivity disorder (ADHD), autism, psychiatric, omega-3, n-3, docosahexaenoic acid and eicosapentaenoic acid. Further studies were identified from the bibliographies of published reviews. Results:  One small randomized controlled trial with LCn-3PUFA supplementation in depression in children found a small beneficial effect over placebo. Four placebo-controlled trials showed uncertain benefit of LCn-3PUFA for ADHD. Single placebo-controlled trials showed no benefit in autism or bipolar disorder. There is an absence of studies examining benefit for first-episode psychosis or schizophrenia in children and adolescents. Conclusions:  While children and adolescents are receiving LCn-3PUFA for a range of psychiatric indications, there is only evidence of likely benefit for unipolar depression.
Publication Type: Journal Article
Source of Publication: Acta Neuropsychiatrica, 19(2), p. 92-103
Publisher: Wiley-Blackwell Publishing Inc
Place of Publication: United States of America
ISSN: 1601-5215
0924-2708
Field of Research (FOR): 170106 Health, Clinical and Counselling Psychology
Socio-Economic Outcome Codes: 920410 Mental Health
920411 Nutrition
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Statistics to Oct 2018: Visitors: 136
Views: 135
Downloads: 0
Appears in Collections:Journal Article

Files in This Item:
2 files
File Description SizeFormat 
Show full item record

SCOPUSTM   
Citations

26
checked on Nov 30, 2018

Page view(s)

76
checked on Mar 4, 2019
Google Media

Google ScholarTM

Check

Altmetric


Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.