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https://hdl.handle.net/1959.11/8314
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DC Field | Value | Language |
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dc.contributor.author | Hanstock, Tanya | en |
dc.contributor.author | Hinreth, SJ | en |
dc.contributor.author | Hazell, PL | en |
dc.contributor.author | Kable, CJ | en |
dc.contributor.author | Clayton, EH | en |
dc.date.accessioned | 2011-08-03T16:04:00Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Australasian Medical Journal, 3(1), p. 131-131 | en |
dc.identifier.issn | 1836-1935 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/8314 | - |
dc.description.abstract | Background: Neurocognitive deficits are reported in participants with juvenile Bipolar Disorder (JBD) including digit span. Digit span is an indicator of short-term auditory memory, working memory, concentration and attention. Long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are important to brain development and functioning, however, their effects on neurocognitive function are not clear. Objective: To examine the effectiveness of LCn-PUFA supplementation on digit span ability in children and adolescents with JBD. Design: Fifteen participants with JBD (9-18 yr) consumed LCn-3PUFA supplements containing 360 mg day-1 eicosapentaenoic acid (EPA) and 1560 mg day-1 docosahexaenoic acid (DHA) for 6 weeks in an open-label preliminary study. Digit span and red blood cell (RBC) LCn-3PUFA concentrations were assessed prior to and following supplementation. Outcomes: Digit Backwards (2.3 ± 0.45 vs 3.2 ± 0.46, p = 0.010) and Scaled Overall Digit Span (11.1 ± 0.70 vs 12.1 ± 0.72, p = 0.046) significantly improved following supplementation. RBC DHA was significantly positively correlated to longest digit span backwards (r = 0.84, p < 0.001) and overall digit span scaled scores (r = 0.62, p = 0.010). Conclusions: Supplementation with LCn-3PUFA was associated with improvements in neurocognitive functioning. Further studies should examine other neuropsychological outcomes in a larger sample in a randomised controlled trial (RCT) and whether cognitive deficits associated with JBD can be prevented. | en |
dc.language | en | en |
dc.publisher | Australasian Medical Journal Pty Ltd | en |
dc.relation.ispartof | Australasian Medical Journal | en |
dc.title | Digit span improvement following long chain omega-3 polyunsaturated fatty acids supplementation: A preliminary study | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.4066/AMJ.2010.209 | en |
dc.subject.keywords | Health, Clinical and Counselling Psychology | en |
local.contributor.firstname | Tanya | en |
local.contributor.firstname | SJ | en |
local.contributor.firstname | PL | en |
local.contributor.firstname | CJ | en |
local.contributor.firstname | EH | en |
local.subject.for2008 | 170106 Health, Clinical and Counselling Psychology | en |
local.subject.seo2008 | 920410 Mental Health | en |
local.profile.school | Psychology | en |
local.profile.school | Psychology | en |
local.profile.school | Psychology | en |
local.profile.school | Psychology | en |
local.profile.school | Psychology | en |
local.profile.email | thansto2@une.edu.au | en |
local.output.category | C4 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | une-20110331-13352 | en |
local.publisher.place | Australia | en |
local.format.startpage | 131 | en |
local.format.endpage | 131 | en |
local.identifier.volume | 3 | en |
local.identifier.issue | 1 | en |
local.title.subtitle | A preliminary study | en |
local.contributor.lastname | Hanstock | en |
local.contributor.lastname | Hinreth | en |
local.contributor.lastname | Hazell | en |
local.contributor.lastname | Kable | en |
local.contributor.lastname | Clayton | en |
dc.identifier.staff | une-id:thansto2 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:8489 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Digit span improvement following long chain omega-3 polyunsaturated fatty acids supplementation | en |
local.output.categorydescription | C4 Letter of Note | en |
local.search.author | Hanstock, Tanya | en |
local.search.author | Hinreth, SJ | en |
local.search.author | Hazell, PL | en |
local.search.author | Kable, CJ | en |
local.search.author | Clayton, EH | en |
local.uneassociation | Unknown | en |
local.year.published | 2010 | en |
Appears in Collections: | Journal Article |
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