1. Research UNE
  2. UNE
  3. Journal Article
Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/8310
Full metadata record
DC FieldValueLanguage
dc.contributor.authorClayton, EHen
dc.contributor.authorHanstock, Tanyaen
dc.contributor.authorHirneth, SJen
dc.contributor.authorKable, CJen
dc.contributor.authorGarg, MLen
dc.contributor.authorHazell, PLen
dc.date.accessioned2011-08-03T14:52:00Z-
dc.date.issued2009-
dc.identifier.citationEuropean Journal of Clinical Nutrition, 63(8), p. 1037-1040en
dc.identifier.issn1476-5640en
dc.identifier.issn0954-3007en
dc.identifier.urihttps://hdl.handle.net/1959.11/8310-
dc.description.abstractLong-chain ω-3 polyunsaturated fatty acid (LCn-3PUFA) supplementation may improve symptoms of depression in children and bipolar disorder (BD) in adults. No studies have examined the effectiveness of LCn-3PUFA supplementation in the treatment of mania and depression in juvenile BD (JBD) when given as an adjunct to standard pharmacological treatment. Eighteen children and adolescents with JBD received supplements containing 360 mg per day eicosapentaenoic acid (EPA) and 1560 mg per day docosahexaenoic acid (DHA) for 6 weeks in an open-label study. Intake and fasting red blood cell (RBC) LCn-3PUFA, mania, depression and global function were assessed before and after supplementation. RBC EPA and DHA were significantly higher following supplementation. Clinician ratings of mania and depression were significantly lower and global functioning significantly higher after supplementation. Parent ratings of internalizing and externalizing behaviours were also significantly lower following supplementation. A larger randomized controlled trial appears warranted in this participant population.en
dc.languageenen
dc.publisherNature Publishing Groupen
dc.relation.ispartofEuropean Journal of Clinical Nutritionen
dc.titleReduced mania and depression in juvenile bipolar disorder associated with long-chain w-3 polyunsaturated fatty acid supplementationen
dc.typeJournal Articleen
dc.identifier.doi10.1038/ejcn.2008.81en
dc.subject.keywordsHealth, Clinical and Counselling Psychologyen
local.contributor.firstnameEHen
local.contributor.firstnameTanyaen
local.contributor.firstnameSJen
local.contributor.firstnameCJen
local.contributor.firstnameMLen
local.contributor.firstnamePLen
local.subject.for2008170106 Health, Clinical and Counselling Psychologyen
local.subject.seo2008920410 Mental Healthen
local.subject.seo2008920411 Nutritionen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.schoolPsychologyen
local.profile.emailthansto2@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20110331-140550en
local.publisher.placeUnited Kingdomen
local.format.startpage1037en
local.format.endpage1040en
local.peerreviewedYesen
local.identifier.volume63en
local.identifier.issue8en
local.contributor.lastnameClaytonen
local.contributor.lastnameHanstocken
local.contributor.lastnameHirnethen
local.contributor.lastnameKableen
local.contributor.lastnameGargen
local.contributor.lastnameHazellen
dc.identifier.staffune-id:thansto2en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:8485en
dc.identifier.academiclevelAcademicen
local.title.maintitleReduced mania and depression in juvenile bipolar disorder associated with long-chain w-3 polyunsaturated fatty acid supplementationen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorClayton, EHen
local.search.authorHanstock, Tanyaen
local.search.authorHirneth, SJen
local.search.authorKable, CJen
local.search.authorGarg, MLen
local.search.authorHazell, PLen
local.uneassociationUnknownen
local.identifier.wosid000268650100015en
local.year.published2009en
Appears in Collections:Journal Article
Files in This Item:
2 files
File Description SizeFormat 
Show simple item record
Google Media

Google ScholarTM

Check

Altmetric


Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.